N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3
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Structure-Activity Relationships and X-ray Structures Describing the Selectivity of Aminopyrazole Inhibitors for c-Jun N-terminal Kinase 3 (JNK3) over p38Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitorsSynthesis, Biological Evaluation, X-ray Structure, and Pharmacokinetics of Aminopyrimidine c-jun-N-terminal Kinase (JNK) InhibitorsDiscovery of Potent and Selective Covalent Inhibitors of JNKProfile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assaysDesign and synthesis of highly potent and isoform selective JNK3 inhibitors: SAR studies on aminopyrazole derivatives.Structural basis and biological consequences for JNK2/3 isoform selective aminopyrazoles.JNK pathway signaling: a novel and smarter therapeutic targets for various biological diseases.The Gewald multicomponent reaction.A guide to picking the most selective kinase inhibitor tool compounds for pharmacological validation of drug targets.Synthesis and SAR of novel isoxazoles as potent c-jun N-terminal kinase (JNK) inhibitors.Synthesis and SAR of novel quinazolines as potent and brain-penetrant c-jun N-terminal kinase (JNK) inhibitorsSynthesis and SAR of 4-(pyrazol-3-yl)-pyridines as novel c-jun N-terminal kinase inhibitorsGalloyl benzamide-based compounds modulating tumour necrosis factor α-stimulated c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signalling pathways.Unprecedently Large-Scale Kinase Inhibitor Set Enabling the Accurate Prediction of Compound-Kinase Activities: A Way toward Selective Promiscuity by Design?Design, synthesis, and structure-activity relationship studies of thiophene-3-carboxamide derivatives as dual inhibitors of the c-Jun N-terminal kinase.The stress kinase JNK regulates gap junction Cx43 gene expression and promotes atrial fibrillation in the aged heart.DBU-mediated [4 + 1] annulations of donor-acceptor cyclopropanes with carbon disulfide or thiourea for synthesis of 2-aminothiophene-3-carboxylates.Stress Signaling JNK2 Crosstalk with CaMKII Underlies Enhanced Atrial Arrhythmogenesis.Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIIδ expression in the aged atrium.Reversine inhibits Colon Carcinoma Cell Migration by Targeting JNK1
P2860
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P2860
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
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2007年の論文
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2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
name
N-(3-Cyano-4,5,6,7-tetrahydro- ...... e, inhibitors of JNK2 and JNK3
@ast
N-(3-Cyano-4,5,6,7-tetrahydro- ...... e, inhibitors of JNK2 and JNK3
@en
N-(3-Cyano-4,5,6,7-tetrahydro- ...... e, inhibitors of JNK2 and JNK3
@nl
type
label
N-(3-Cyano-4,5,6,7-tetrahydro- ...... e, inhibitors of JNK2 and JNK3
@ast
N-(3-Cyano-4,5,6,7-tetrahydro- ...... e, inhibitors of JNK2 and JNK3
@en
N-(3-Cyano-4,5,6,7-tetrahydro- ...... e, inhibitors of JNK2 and JNK3
@nl
prefLabel
N-(3-Cyano-4,5,6,7-tetrahydro- ...... e, inhibitors of JNK2 and JNK3
@ast
N-(3-Cyano-4,5,6,7-tetrahydro- ...... e, inhibitors of JNK2 and JNK3
@en
N-(3-Cyano-4,5,6,7-tetrahydro- ...... e, inhibitors of JNK2 and JNK3
@nl
P2093
P1476
N-(3-Cyano-4,5,6,7-tetrahydro- ...... e, inhibitors of JNK2 and JNK3
@en
P2093
Allison K Dunn
Donald O Somers
Gladstone Thompson
James R Musgrave
Jeffery L Smith
John A Christopher
Kendra E Hightower
Margarete Neu
Maria Cichy-Knight
Murray J Brown
P304
P356
10.1016/J.BMCL.2006.12.003
P407
P577
2006-12-15T00:00:00Z