The structure of human collapsin response mediator protein 2, a regulator of axonal growth
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Structures of BIR domains from human NAIP and cIAP2The crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimerCrystal and solution structure, stability and post-translational modifications of collapsin response mediator protein 2Completing the family portrait of the anti-apoptotic Bcl-2 proteins: crystal structure of human Bfl-1 in complex with BimInsights into the oligomerization of CRMPs: crystal structure of human collapsin response mediator protein 5Crystal structure of human CRMP-4: correction of intensities for lattice-translocation disorderCollapsin response mediator protein 2: high-resolution crystal structure sheds light on small-molecule binding, post-translational modifications, and conformational flexibility.Leucine-rich repeat kinase 2 (LRRK2): a key player in the pathogenesis of Parkinson's diseaseThe functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowthCollapsin response mediator proteins regulate neuronal development and plasticity by switching their phosphorylation status.Identification and structural analysis of C-terminally truncated collapsin response mediator protein-2 in a murine model of prion diseases.Models for LRRK2-Linked Parkinsonism.Collapsin response mediator protein-2 is a calmodulin-binding proteinCRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon ElongationA collapsin response mediator protein 2 isoform controls myosin II-mediated cell migration and matrix assembly by trapping ROCK II.Collapsin response mediator protein-2 phosphorylation promotes the reversible retraction of oligodendrocyte processes in response to non-lethal oxidative stress.Divergent functions through alternative splicing: the Drosophila CRMP gene in pyrimidine metabolism, brain, and behavior.Opening Pandora's jar: a primer on the putative roles of CRMP2 in a panoply of neurodegenerative, sensory and motor neuron, and central disorders.SUMOylation alters CRMP2 regulation of calcium influx in sensory neurons.Collapsin Response Mediator Protein-2 (CRMP2) is a Plausible Etiological Factor and Potential Therapeutic Target in Alzheimer's Disease: Comparison and Contrast with Microtubule-Associated Protein TauCRMP2 protein SUMOylation modulates NaV1.7 channel trafficking.Phosphorylation and mRNA splicing of collapsin response mediator protein-2 determine inhibition of rho-associated protein kinase (ROCK) II function in carcinoma cell migration and invasion.Regulation of intracellular signalling through cysteine oxidation by reactive oxygen species.Building complexity: insights into self-organized assembly of microtubule-based architecturesMolecular dynamics simulations and in vitro analysis of the CRMP2 thiol switch.CRMPs Function in Neurons and Glial Cells: Potential Therapeutic Targets for Neurodegenerative Diseases and CNS Injury.Drug binding assays do not reveal specific binding of lacosamide to collapsin response mediator protein 2 (CRMP-2).Semaphorin3A signaling mediated by Fyn-dependent tyrosine phosphorylation of collapsin response mediator protein 2 at tyrosine 32.Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.Structure of human collapsin response mediator protein 1: a possible role of its C-terminal tail.A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors.Structural basis for CRMP2-induced axonal microtubule formation.Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration.Collapsin response mediator proteins (CRMPs) are a new class of microtubule-associated protein (MAP) that selectively interacts with assembled microtubules via a taxol-sensitive binding interaction.Processing and nuclear localization of CRMP2 during brain development induce neurite outgrowth inhibition.Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5.SUMO on CRMPs - wrestling for pain?The memory enhancing effect of the APP-derived tripeptide Ac-rER is mediated through CRMP2.
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The structure of human collapsin response mediator protein 2, a regulator of axonal growth
description
2007 nî lūn-bûn
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2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
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2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The structure of human collaps ...... , a regulator of axonal growth
@ast
The structure of human collaps ...... , a regulator of axonal growth
@en
The structure of human collaps ...... , a regulator of axonal growth
@nl
type
label
The structure of human collaps ...... , a regulator of axonal growth
@ast
The structure of human collaps ...... , a regulator of axonal growth
@en
The structure of human collaps ...... , a regulator of axonal growth
@nl
prefLabel
The structure of human collaps ...... , a regulator of axonal growth
@ast
The structure of human collaps ...... , a regulator of axonal growth
@en
The structure of human collaps ...... , a regulator of axonal growth
@nl
P2093
P2860
P50
P3181
P1476
The structure of human collaps ...... , a regulator of axonal growth
@en
P2093
Alex Flores
Petri Kursula
P2860
P304
P3181
P356
10.1111/J.1471-4159.2006.04401.X
P407
P577
2007-05-01T00:00:00Z