Rational Conversion of Substrate and Product Specificity in a Salvia Monoterpene Synthase: Structural Insights into the Evolution of Terpene Synthase Function - Test2 - elhamkhani - TriplyDB

Rational Conversion of Substrate and Product Specificity in a Salvia Monoterpene Synthase: Structural Insights into the Evolution of Terpene Synthase Function

Rational Conversion of Substrate and Product Specificity in a Salvia Monoterpene Synthase: Structural Insights into the Evolution of Terpene Synthase Function

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The primary diterpene synthase products of Picea abies levopimaradiene/abietadiene synthase (PaLAS) are epimers of a thermally unstable diterpenol Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases Isoprene emission from plants: why and how Accessing Nature's diversity through metabolic engineering and synthetic biology Crystal Structure of (+)-δ-Cadinene Synthase from Gossypium arboreum and Evolutionary Divergence of Metal Binding Motifs for Catalysis Insights into Diterpene Cyclization from Structure of Bifunctional Abietadiene Synthase from Abies grandis Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency Biosynthesis of hydrocarbons and volatile organic compounds by fungi: bioengineering potential Identification of a fungal 1,8-cineole synthase from Hypoxylon sp. with specificity determinants in common with the plant synthases The α-Terpineol to 1,8-Cineole Cyclization Reaction of Tobacco Terpene Synthases.Expression, crystallization and structure elucidation of γ-terpinene synthase from Thymus vulgaris.EST analysis and annotation of transcripts derived from a trichome-specific cDNA library from Salvia fruticosa.Plasticity and evolution of (+)-3-carene synthase and (-)-sabinene synthase functions of a sitka spruce monoterpene synthase gene family associated with weevil resistance.An integrated genomic, proteomic and biochemical analysis of (+)-3-carene biosynthesis in Sitka spruce (Picea sitchensis) genotypes that are resistant or susceptible to white pine weevil.Sandalwood fragrance biosynthesis involves sesquiterpene synthases of both the terpene synthase (TPS)-a and TPS-b subfamilies, including santalene synthases.Cloning, functional characterization and genomic organization of 1,8-cineole synthases from Lavandula.Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids.Explaining intraspecific diversity in plant secondary metabolites in an ecological context.Biochemical characterization and homology modeling of methylbutenol synthase and implications for understanding hemiterpene synthase evolution in plants.Predicting the functions and specificity of triterpenoid synthases: a mechanism-based multi-intermediate docking approach.Terpene Specialized Metabolism in Arabidopsis thaliana Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.One amino acid makes the difference: the formation of ent-kaurene and 16α-hydroxy-ent-kaurane by diterpene synthases in poplar Combined metabolome and transcriptome profiling provides new insights into diterpene biosynthesis in S. pomifera glandular trichomes Isolation and Characterization of Three New Monoterpene Synthases from Artemisia annua.Terpenoid synthase structures: a so far incomplete view of complex catalysis.In Planta Recapitulation of Isoprene Synthases Evolution from Ocimene Synthases.Functional plasticity of paralogous diterpene synthases involved in conifer defense.Production of the forskolin precursor 11β-hydroxy-manoyl oxide in yeast using surrogate enzymatic activities.Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase Contrasting ontogenetic trajectories for phenolic and terpenoid defences in Eucalyptus froggattii.Constructing de novo biosynthetic pathways for chemical synthesis inside living cells.Analysis of plant leaf metabolites reveals no common response to insect herbivory by Pieris rapae in three related host-plant species Enzyme (re)design: lessons from natural evolution and computation.Transcriptomic insight into terpenoid and carbazole alkaloid biosynthesis, and functional characterization of two terpene synthases in curry tree (Murraya koenigii)Protein engineering towards natural product synthesis and diversification.Terpenoid biosynthesis in trichomes--current status and future opportunities.From flavors and pharmaceuticals to advanced biofuels: production of isoprenoids in Saccharomyces cerevisiae.Developing a yeast cell factory for the production of terpenoids.Photosynthetic terpene hydrocarbon production for fuels and chemicals.

P2860

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Rational Conversion of Substrate and Product Specificity in a Salvia Monoterpene Synthase: Structural Insights into the Evolution of Terpene Synthase Function

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2007 nî lūn-bûn

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Walid Mahrez

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Bornyl diphosphate synthase: structure and strategy for carbocation manipulation by a terpenoid cyclase.

Plant terpenoid synthases: molecular biology and phylogenetic analysis

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Crystal structure determination of aristolochene synthase from the blue cheese mold, Penicillium roqueforti

Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade

Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase

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Automated protein model building combined with iterative structure refinement

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

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