Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases
about
Predictability of evolutionary trajectories in fitness landscapesStructure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulationWhat can we learn from fitness landscapes?The causes of epistasisFollowing evolutionary paths to protein-protein interactions with high affinity and selectivityIdentification and analysis of residues contained on β → α loops of the dual-substrate (βα)8phosphoribosyl isomerase A specific for its phosphoribosyl anthranilate isomerase activityStructure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates ,Structural Elucidation of Cisoid and Transoid Cyclization Pathways of a Sesquiterpene Synthase Using 2-Fluorofarnesyl DiphosphatesAn Engineered Monolignol 4-O-Methyltransferase Depresses Lignin Biosynthesis and Confers Novel Metabolic Capability in ArabidopsisReprogramming the Chemodiversity of Terpenoid Cyclization by Remolding the Active Site Contour of epi -Isozizaene SynthaseRational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiencyBiosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutantsAnalyzing protein structure and function using ancestral gene reconstructionA high-throughput colorimetric screening assay for terpene synthase activity based on substrate consumptionDiterpene cyclases and the nature of the isoprene foldIdentification and biosynthesis of acylphloroglucinols in Hypericum gentianoidesProtein change in plant evolution: tracing one thread connecting molecular and phenotypic diversityThe rise of chemodiversity in plants.Natural variation in monoterpene synthesis in kiwifruit: transcriptional regulation of terpene synthases by NAC and ETHYLENE-INSENSITIVE3-like transcription factors.Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control.Functional annotation, genome organization and phylogeny of the grapevine (Vitis vinifera) terpene synthase gene family based on genome assembly, FLcDNA cloning, and enzyme assays.Inferring fitness landscapes by regression produces biased estimates of epistasis.Transcriptome mining, functional characterization, and phylogeny of a large terpene synthase gene family in spruce (Picea spp.).Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers.Selectivity of fungal sesquiterpene synthases: role of the active site's H-1 alpha loop in catalysisExploring the complexity of the HIV-1 fitness landscape.Positive Darwinian selection is a driving force for the diversification of terpenoid biosynthesis in the genus Oryza.Engineering synthetic recursive pathways to generate non-natural small molecules.Evolutionary biochemistry: revealing the historical and physical causes of protein properties.Replaying the tape of life: quantification of the predictability of evolution.Use of nonionic surfactants for improvement of terpene production in Saccharomyces cerevisiae.Total (bio)synthesis: strategies of nature and of chemists.Should evolutionary geneticists worry about higher-order epistasis?Quantifying the similarity of monotonic trajectories in rough and smooth fitness landscapes.Properties of selected mutations and genotypic landscapes under Fisher's geometric model.Genetic variation of adenylation domains of the anabaenopeptin synthesis operon and evolution of substrate promiscuity.Variation in capsidiol sensitivity between Phytophthora infestans and Phytophthora capsici is consistent with their host range.Comparative analysis and validation of the malachite green assay for the high throughput biochemical characterization of terpene synthases.Terpene Specialized Metabolism in Arabidopsis thalianaQuantitative Description of a Protein Fitness Landscape Based on Molecular Features.
P2860
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P2860
Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Quantitative exploration of th ...... plant sesquiterpene synthases
@ast
Quantitative exploration of th ...... plant sesquiterpene synthases
@en
Quantitative exploration of th ...... plant sesquiterpene synthases
@nl
type
label
Quantitative exploration of th ...... plant sesquiterpene synthases
@ast
Quantitative exploration of th ...... plant sesquiterpene synthases
@en
Quantitative exploration of th ...... plant sesquiterpene synthases
@nl
prefLabel
Quantitative exploration of th ...... plant sesquiterpene synthases
@ast
Quantitative exploration of th ...... plant sesquiterpene synthases
@en
Quantitative exploration of th ...... plant sesquiterpene synthases
@nl
P2093
P2860
P3181
P356
P1476
Quantitative exploration of th ...... plant sesquiterpene synthases
@en
P2093
Arthur Malone
B Andes Hess
Bryan T Greenhagen
Iseult Sheehan
Joe Chappell
Joseph P Noel
Lidia Smentek
Nikki Dellas
Paul E O'Maille
P2860
P2888
P304
P3181
P356
10.1038/NCHEMBIO.113
P407
P577
2008-10-01T00:00:00Z
P5875
P6179
1002004543