Inhibition of the Mycobacterium tuberculosis enoyl acyl carrier protein reductase InhA by arylamides
about
A virtual screen discovers novel, fragment-sized inhibitors of Mycobacterium tuberculosis InhAPyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhADrug discovery using chemical systems biology: repositioning the safe medicine Comtan to treat multi-drug and extensively drug resistant tuberculosisDiscovery of Mycobacterium tuberculosis InhA Inhibitors by Binding Sites Comparison and Ligands Prediction.MycPermCheck: the Mycobacterium tuberculosis permeability prediction tool for small molecules.High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv.Novel inhibitors of InhA efficiently kill Mycobacterium tuberculosis under aerobic and anaerobic conditions.Computer-Aided Design of Orally Bioavailable Pyrrolidine Carboxamide Inhibitors of Enoyl-Acyl Carrier Protein Reductase of Mycobacterium tuberculosis with Favorable Pharmacokinetic Profiles.Recent advances in the design and synthesis of heterocycles as anti-tubercular agents.Tuberculosis drugs: new candidates and how to find more.Targeting InhA, the FASII enoyl-ACP reductase: SAR studies on novel inhibitor scaffolds.Recent advances in inhibitors of bacterial fatty acid synthesis type II (FASII) system enzymes as potential antibacterial agents.Mycobacterium tuberculosis enoyl-acyl carrier protein reductase inhibitors as potential antituberculotics: development in the past decade.Recent Advances and Structural Features of Enoyl-ACP Reductase Inhibitors of Mycobacterium tuberculosis.Key Structures and Interactions for Binding of Mycobacterium tuberculosis Protein Kinase B Inhibitors from Molecular Dynamics Simulation.Insights into the bonding pattern for characterizing the open and closed state of the substrate-binding loop in Mycobacterium tuberculosis InhA.Discovery of novel InhA reductase inhibitors: application of pharmacophore- and shape-based screening approach.Cell wall permeability assisted virtual screening to identify potential direct InhA inhibitors of Mycobacterium tuberculosis and their biological evaluation.Characterization of MymA protein as a flavin-containing monooxygenase and as a target of isoniazid.Identification of InhA inhibitors: A combination of virtual screening, molecular dynamics simulations and quantum chemical studies.Die Fettsäuresynthese als Angriffspunkt
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P2860
Inhibition of the Mycobacterium tuberculosis enoyl acyl carrier protein reductase InhA by arylamides
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Inhibition of the Mycobacteriu ...... n reductase InhA by arylamides
@ast
Inhibition of the Mycobacteriu ...... n reductase InhA by arylamides
@en
Inhibition of the Mycobacteriu ...... n reductase InhA by arylamides
@nl
type
label
Inhibition of the Mycobacteriu ...... n reductase InhA by arylamides
@ast
Inhibition of the Mycobacteriu ...... n reductase InhA by arylamides
@en
Inhibition of the Mycobacteriu ...... n reductase InhA by arylamides
@nl
prefLabel
Inhibition of the Mycobacteriu ...... n reductase InhA by arylamides
@ast
Inhibition of the Mycobacteriu ...... n reductase InhA by arylamides
@en
Inhibition of the Mycobacteriu ...... n reductase InhA by arylamides
@nl
P2093
P2860
P1476
Inhibition of the Mycobacteriu ...... n reductase InhA by arylamides
@en
P2093
Akram Alian
Paul R Ortiz de Montellano
P2860
P304
P356
10.1016/J.BMC.2007.08.013
P407
P577
2007-11-01T00:00:00Z