Crystal structures of the N-terminal kinase domain of human RSK1 bound to three different ligands: Implications for the design of RSK1 specific inhibitors
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The Crystal Structures of Substrate and Nucleotide Complexes of Enterococcus faecium Aminoglycoside-2''-Phosphotransferase-IIa [APH(2'')-IIa] Provide Insights into Substrate Selectivity in the APH(2'') SubfamilyStructural Basis of Human p70 Ribosomal S6 Kinase-1 Regulation by Activation Loop PhosphorylationStructural Diversity of the Active N-Terminal Kinase Domain of p90 Ribosomal S6 Kinase 2Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domainInsights into the inhibition of the p90 ribosomal S6 kinase (RSK) by the flavonol glycoside SL0101 from the 1.5 Å crystal structure of the N-terminal domain of RSK2 with bound inhibitor.Structural basis for the autoinhibition of the C-terminal kinase domain of human RSK1RSK3: A regulator of pathological cardiac remodelingLocalization and retention of p90 ribosomal S6 kinase 1 in the nucleus: implications for its functionThe unusual mechanism of inhibition of the p90 ribosomal S6 kinase (RSK) by flavonol rhamnosides.RSK2 Binding Models Delineate Key Features for Activityp90 ribosomal S6 kinase 1 (RSK1) and the catalytic subunit of protein kinase A (PKA) compete for binding the pseudosubstrate region of PKAR1alpha: role in the regulation of PKA and RSK1 activities.Molecular basis for small molecule inhibition of G protein-coupled receptor kinasesStructural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY.A Rising Cancer Prevention Target of RSK2 in Human Skin Cancer.Identification of domains responsible for ubiquitin-dependent degradation of dMyc by glycogen synthase kinase 3beta and casein kinase 1 kinasesSynthetic lethality screen identifies RPS6KA2 as modifier of epidermal growth factor receptor activity in pancreatic cancer.A regulatory mechanism for RSK2 NH(2)-terminal kinase activity.Allosteric regulation of PKCθ: understanding multistep phosphorylation and priming by ligands in AGC kinases.TAK1 inhibition in the DFG-out conformation.Functional Basis and Biophysical Approaches to Characterize the C-Terminal Domain of Human-Ribosomal S6 Kinases-3.
P2860
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P2860
Crystal structures of the N-terminal kinase domain of human RSK1 bound to three different ligands: Implications for the design of RSK1 specific inhibitors
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Crystal structures of the N-te ...... gn of RSK1 specific inhibitors
@ast
Crystal structures of the N-te ...... gn of RSK1 specific inhibitors
@en
Crystal structures of the N-te ...... gn of RSK1 specific inhibitors
@nl
type
label
Crystal structures of the N-te ...... gn of RSK1 specific inhibitors
@ast
Crystal structures of the N-te ...... gn of RSK1 specific inhibitors
@en
Crystal structures of the N-te ...... gn of RSK1 specific inhibitors
@nl
prefLabel
Crystal structures of the N-te ...... gn of RSK1 specific inhibitors
@ast
Crystal structures of the N-te ...... gn of RSK1 specific inhibitors
@en
Crystal structures of the N-te ...... gn of RSK1 specific inhibitors
@nl
P2093
P2860
P356
P1433
P1476
Crystal structures of the N-te ...... gn of RSK1 specific inhibitors
@en
P2093
Hidehito Kotani
John C Reid
Mari Ikuta
Maria Kornienko
Noel Byrne
Sanjeev K Munshi
Shinji Mizuarai
P2860
P304
P356
10.1110/PS.073123707
P577
2007-12-01T00:00:00Z