Mechanism of transcriptional stalling at cisplatin-damaged DNA
about
Structure-function studies of the RNA polymerase II elongation complexTranscription Blockage Leads to New BeginningsTranscriptional mutagenesis and its potential roles in the etiology of cancer and bacterial antibiotic resistanceMammalian transcription-coupled excision repairStructural basis of transcription inhibition by alpha-amanitin and implications for RNA polymerase II translocationcis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospectsMolecular Basis of Transcriptional Mutagenesis at 8-OxoguanineX-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adductMechanism of Translesion Transcription by RNA Polymerase II and Its Role in Cellular Resistance to DNA DamageTranscription-coupled DNA repair: two decades of progress and surprisesMutations in Cockayne Syndrome-Associated Genes (Csa and Csb) Predispose to Cisplatin-Induced Hearing Loss in Mice.Templated nucleoside triphosphate binding to a noncatalytic site on RNA polymerase regulates transcription.Rapid cross-linking of an RNA internal loop by the anticancer drug cisplatinRad26p, a transcription-coupled repair factor, is recruited to the site of DNA lesion in an elongating RNA polymerase II-dependent manner in vivoInsights into how Spt5 functions in transcription elongation and repressing transcription coupled DNA repair.Binding of kinetically inert metal ions to RNA: the case of platinum(II).Chromatin Regulates Genome Targeting with Cisplatin.Transcription inhibition by platinum-DNA cross-links in live mammalian cells.Synergistic effects of cisplatin chemotherapy and gold nanorod-mediated hyperthermia on ovarian cancer cells and tumors.Nucleotide excision repair in Trypanosoma brucei: specialization of transcription-coupled repair due to multigenic transcriptionCellular responses to Cisplatin-induced DNA damage.Understanding and improving platinum anticancer drugs--phenanthriplatinConformation and recognition of DNA modified by a new antitumor dinuclear PtII complex resistant to decomposition by sulfur nucleophiles.Role of endonucleases XPF and XPG in nucleotide excision repair of platinated DNA and cisplatin/oxaliplatin cytotoxicity.An adsorptive transfer technique coupled with brdicka reaction to reveal the importance of metallothionein in chemotherapy with platinum based cytostatics.Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.Replacement of a thiourea with an amidine group in a monofunctional platinum-acridine antitumor agent. Effect on DNA interactions, DNA adduct recognition and repair.Monofunctional platinum-DNA adducts are strong inhibitors of transcription and substrates for nucleotide excision repair in live mammalian cellsT7 RNA polymerases backed up by covalently trapped proteins catalyze highly error prone transcriptionLack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts.UV damage regulates alternative polyadenylation of the RPB2 gene in yeast.Structures of E. coli σS-transcription initiation complexes provide new insights into polymerase mechanism.Transcriptional mutagenesis: causes and involvement in tumour development.Transcription of DNA containing the 5-guanidino-4-nitroimidazole lesion by human RNA polymerase II and bacteriophage T7 RNA polymerase.Inhibition of transcription by platinum antitumor compoundsForks, pincers, and triggers: the tools for nucleotide incorporation and translocation in multi-subunit RNA polymerases.Host Cell Reactivation and Transcriptional Activation of Carboplatin-Modified BRCA1.Common Chemical Inductors of Replication Stress: Focus on Cell-Based Studies.Towards molecular systems biology of gene transcription and regulation.Basic mechanisms of RNA polymerase II activity and alteration of gene expression in Saccharomyces cerevisiae.
P2860
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P2860
Mechanism of transcriptional stalling at cisplatin-damaged DNA
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Mechanism of transcriptional stalling at cisplatin-damaged DNA
@ast
Mechanism of transcriptional stalling at cisplatin-damaged DNA
@en
Mechanism of transcriptional stalling at cisplatin-damaged DNA
@nl
type
label
Mechanism of transcriptional stalling at cisplatin-damaged DNA
@ast
Mechanism of transcriptional stalling at cisplatin-damaged DNA
@en
Mechanism of transcriptional stalling at cisplatin-damaged DNA
@nl
prefLabel
Mechanism of transcriptional stalling at cisplatin-damaged DNA
@ast
Mechanism of transcriptional stalling at cisplatin-damaged DNA
@en
Mechanism of transcriptional stalling at cisplatin-damaged DNA
@nl
P2093
P356
P1476
Mechanism of transcriptional stalling at cisplatin-damaged DNA
@en
P2093
Florian Brueckner
Gerke E Damsma
Patrick Cramer
P2860
P2888
P304
P356
10.1038/NSMB1314
P577
2007-12-01T00:00:00Z
P5875
P6179
1021435683