Mechanism of Translesion Transcription by RNA Polymerase II and Its Role in Cellular Resistance to DNA Damage - Test2 - elhamkhani - TriplyDB

Mechanism of Translesion Transcription by RNA Polymerase II and Its Role in Cellular Resistance to DNA Damage

Mechanism of Translesion Transcription by RNA Polymerase II and Its Role in Cellular Resistance to DNA Damage

http://www.wikidata.org/entity/Q27677970

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Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase.Effect of a monofunctional phenanthriplatin-DNA adduct on RNA polymerase II transcriptional fidelity and translesion synthesis Transcriptional mutagenesis and its potential roles in the etiology of cancer and bacterial antibiotic resistance Mammalian transcription-coupled excision repair A microchip platform for structural oncology applications.A genetic assay for transcription errors reveals multilayer control of RNA polymerase II fidelity UV light-induced DNA lesions cause dissociation of yeast RNA polymerases-I and establishment of a specialized chromatin structure at rRNA genes.A Molecular Toolkit to Visualize Native Protein Assemblies in the Context of Human Disease Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis.UVB induces a genome-wide acting negative regulatory mechanism that operates at the level of transcription initiation in human cells.Nucleotide excision repair in Trypanosoma brucei: specialization of transcription-coupled repair due to multigenic transcription UV damage-induced RNA polymerase II stalling stimulates H2B deubiquitylation.Transcription elongation. Heterogeneous tracking of RNA polymerase and its biological implications.Transcription bypass of DNA lesions enhances cell survival but attenuates transcription coupled DNA repair.Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.DNA repair and recovery of RNA synthesis following exposure to ultraviolet light are delayed in long genes.Visualizing translocation dynamics and nascent transcript errors in paused RNA polymerases in vivo.Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.Autologous hematopoietic stem cell transplantation in lymphoma patients is associated with a decrease in the double strand break repair capacity of peripheral blood lymphocytes The RNA polymerase bridge helix YFI motif in catalysis, fidelity and translocation.Structures of E. coli σS-transcription initiation complexes provide new insights into polymerase mechanism.Functional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitution RNA Polymerase II Trigger Loop Mobility: INDIRECT EFFECTS OF Rpb9.RNA polymerase II acts as a selective sensor for DNA lesions and endogenous DNA modifications Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism Direct assessment of transcription fidelity by high-resolution RNA sequencing.Computational simulation strategies for analysis of multisubunit RNA polymerases.Mechanism of transcription-coupled DNA modification recognition.Basic mechanisms of RNA polymerase II activity and alteration of gene expression in Saccharomyces cerevisiae.Double strand breaks: hurdles for RNA polymerase II transcription?RNA polymerase between lesion bypass and DNA repair.Understanding the Molecular Basis of RNA Polymerase II Transcription.Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis.Gearing up chromatin: A role for chromatin remodeling during the transcriptional restart upon DNA damage RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications.The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro.The Structural Basis of Transcription: 10 Years After the Nobel Prize in Chemistry.Facilitators and Repressors of Transcription-coupled DNA Repair in Saccharomyces cerevisiae.Regulation of nucleotide excision repair by nuclear lamin b1

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Mechanism of Translesion Transcription by RNA Polymerase II and Its Role in Cellular Resistance to DNA Damage

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Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance

The RNA polymerase II trigger loop functions in substrate selection and is directly targeted by alpha-amanitin

Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution

Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage

CPD damage recognition by transcribing RNA polymerase II

Mechanism of transcriptional stalling at cisplatin-damaged DNA

Molecular Basis of Transcriptional Mutagenesis at 8-Oxoguanine

Replication through an abasic DNA lesion: structural basis for adenine selectivity

Structural basis of RNA polymerase II backtracking, arrest and reactivation

VMD: visual molecular dynamics

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