Synthesis and characterization of cytidine derivatives that inhibit the kinase IspE of the non-mevalonate pathway for isoprenoid biosynthesis
about
A triclinic crystal form ofEscherichia coli4-diphosphocytidyl-2C-methyl-D-erythritol kinase and reassessment of the quaternary structureIspE inhibitors identified by a combination of in silico and in vitro high-throughput screeningIsoprenoid precursor biosynthesis offers potential targets for drug discovery against diseases caused by apicomplexan parasitesIdentification of novel small molecule inhibitors of 4-diphosphocytidyl-2-C-methyl-D-erythritol (CDP-ME) kinase of Gram-negative bacteria.The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target.Peptide deformylase--a promising therapeutic target for tuberculosis and antibacterial drug discovery.Biochemistry of the non-mevalonate isoprenoid pathway.In search of new herbicidal inhibitors of the non-mevalonate pathway.Molecular recognition in chemical and biological systems.The MEP pathway and the development of inhibitors as potential anti-infective agents
P2860
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P2860
Synthesis and characterization of cytidine derivatives that inhibit the kinase IspE of the non-mevalonate pathway for isoprenoid biosynthesis
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Synthesis and characterization ...... ay for isoprenoid biosynthesis
@ast
Synthesis and characterization ...... ay for isoprenoid biosynthesis
@en
Synthesis and characterization ...... ay for isoprenoid biosynthesis
@nl
type
label
Synthesis and characterization ...... ay for isoprenoid biosynthesis
@ast
Synthesis and characterization ...... ay for isoprenoid biosynthesis
@en
Synthesis and characterization ...... ay for isoprenoid biosynthesis
@nl
prefLabel
Synthesis and characterization ...... ay for isoprenoid biosynthesis
@ast
Synthesis and characterization ...... ay for isoprenoid biosynthesis
@en
Synthesis and characterization ...... ay for isoprenoid biosynthesis
@nl
P2093
P50
P356
P1433
P1476
Synthesis and characterization ...... ay for isoprenoid biosynthesis
@en
P2093
Anna K H Hirsch
Christine M Crane
Magnus S Alphey
Susan Lauw
Tanja Sgraja
Victoria Illarionova
William N Hunter
P304
P356
10.1002/CMDC.200700208
P577
2008-01-01T00:00:00Z