Structural characterization and pharmacodynamic effects of an orally active 11beta-hydroxysteroid dehydrogenase type 1 inhibitor

Structural characterization and pharmacodynamic effects of an orally active 11beta-hydroxysteroid dehydrogenase type 1 inhibitor

Item
http://www.wikidata.org/entity/Q27649250
11β-Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus.Continuous inhibition of 11β-hydroxysteroid dehydrogenase type I in adipose tissue leads to tachyphylaxis in humans and rats but not in mice.11beta-hydroxysteroid dehydrogenase type 1 inhibitors: a review of recent patents.Crystal structures of 11β-hydroxysteroid dehydrogenase type 1 and their use in drug discovery.Microglial scavenger receptors and their roles in the pathogenesis of Alzheimer's disease.Discovery of adamantyl ethanone derivatives as potent 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors.On-column ligand exchange for structure-based drug design: a case study with human 11β-hydroxysteroid dehydrogenase type 1.2-Allylaminothiazole and 2-allylaminodihydrothiazole derivatives: synthesis, characterization, and evaluation of bioactivity.Glucocorticoid-mediated effects on metabolism are reversed by targeting 11 beta hydroxysteroid dehydrogenase type 1 in human skeletal muscle.Time of the day for 11beta-HSD1 inhibition plays a role in improving glucose homeostasis in DIO mice.11-Beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors in Type 2 diabetes mellitus and obesity
P2860

Structural characterization and pharmacodynamic effects of an orally active 11beta-hydroxysteroid dehydrogenase type 1 inhibitor

Item
http://www.wikidata.org/entity/Q27649250
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
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2008年論文
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2008年論文
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2008年論文
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2008年論文
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2008年論文
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2008年论文
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name
Structural characterization an ...... dehydrogenase type 1 inhibitor
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Structural characterization an ...... dehydrogenase type 1 inhibitor
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Structural characterization an ...... dehydrogenase type 1 inhibitor
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Structural characterization an ...... dehydrogenase type 1 inhibitor
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Structural characterization an ...... dehydrogenase type 1 inhibitor
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Structural characterization an ...... dehydrogenase type 1 inhibitor
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Structural characterization an ...... dehydrogenase type 1 inhibitor
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Structural characterization an ...... dehydrogenase type 1 inhibitor
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Structural characterization an ...... dehydrogenase type 1 inhibitor
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Structural characterization an ...... dehydrogenase type 1 inhibitor
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10.1111/J.1747-0285.2007.00603.X
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