Novel peptide inhibitors for Grb2 SH2 domain and their detection by surface plasmon resonanceOn the origins of enzyme inhibitor selectivity and promiscuity: a case study of protein kinase binding to staurosporineExpanding the number of 'druggable' targets: non-enzymes and protein-protein interactionsSolution structure of a novel ETB receptor selective agonist ET1-21 [Cys(Acm)1,15, Aib3,11, Leu7] by nuclear magnetic resonance spectroscopy and molecular modellingRefined solution structure of omega-conotoxin GVIA: implications for calcium channel bindingNMR structural characterization of cecropin A(1-8) - magainin 2(1-12) and cecropin A (1-8) - melittin (1-12) hybrid peptidesA 30-residue fragment of the carp granulin-1 protein folds into a stack of two beta-hairpins similar to that found in the native proteinStructure of a paralytic peptide from an insect, Manduca sextaConformational mapping of the N-terminal segment of surfactant protein B in lipid using 13C-enhanced Fourier transform infrared spectroscopyStructures of the intradiskal loops and amino terminus of the G-protein receptor, rhodopsinA peptide derived from the C-terminal part of a plant cysteine protease folds into a stack of two beta-hairpins, a scaffold present in the emerging family of granulin-like growth factorsA new B-chain mutant of insulin: comparison with the insulin crystal structure and role of sulfonate groups in the B-chain structureStructure-antigenicity relationship studies of the central conserved region of human respiratory syncytial virus protein GCharacterization and NMR solution structure of a novel cyclic pentapeptide inhibitor of pathogenic hantavirusesDesign of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesisCompensating enthalpic and entropic changes hinder binding affinity optimizationStructure-based drug design of pyrrolidine-1, 2-dicarboxamides as a novel series of orally bioavailable factor Xa inhibitorsDiscovery and design of novel HSP90 inhibitors using multiple fragment-based design strategiesThe discovery of (2R,4R)-N-(4-chlorophenyl)-N- (2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidine-1,2-dicarboxamide (PD 0348292), an orally efficacious factor Xa inhibitorCrystal structure of the T315I mutant of AbI kinaseSelectivity-determining residues in Plk1Structural characterization and pharmacodynamic effects of an orally active 11beta-hydroxysteroid dehydrogenase type 1 inhibitorDevelopment of Broad-Spectrum Halomethyl Ketone Inhibitors Against Coronavirus Main Protease 3CLproCaged Protein Prenyltransferase Substrates: Tools for Understanding Protein PrenylationProbing the Active Site ofCandida glabrataDihydrofolate Reductase with High Resolution Crystal Structures and the Synthesis of New InhibitorsStructural insights for design of potent spleen tyrosine kinase inhibitors from crystallographic analysis of three inhibitor complexesPotent triazolothione inhibitor of heat-shock protein-90The design, synthesis and potential utility of fluorescence probes that target DFG-out conformation of p38alpha for high throughput screening binding assayStructural analysis of DFG-in and DFG-out dual Src-Abl inhibitors sharing a common vinyl purine templateThe X-Ray Structure of Carboxypeptidase A Inhibited by a Thiirane Mechanism-Based InhibitorSynthesis, Properties, and Applications of Diazotrifluropropanoyl-Containing Photoactive Analogs of Farnesyl Diphosphate Containing Modified Linkages for Enhanced StabilityHeme oxygenase inhibition by 2-oxy-substituted 1-azolyl-4-phenylbutanes: effect of variation of the azole moiety. X-ray crystal structure of human heme oxygenase-1 in complex with 4-phenyl-1-(1H-1,2,4-triazol-1-yl)-2-butanoneHow Much Binding Affinity Can be Gained by Filling a Cavity?Crystal structures of IL-2-inducible T cell kinase complexed with inhibitors: insights into rational drug design and activity regulationDesign of potent IGF1-R inhibitors related to bis-azaindolesFragment-Based Screen against HIV ProteaseStructural mechanism of the Pan-BCR-ABL inhibitor ponatinib (AP24534): lessons for overcoming kinase inhibitor resistanceApplying Molecular Dynamics Simulations to Identify Rarely Sampled Ligand-bound Conformational States of Undecaprenyl Pyrophosphate Synthase, an Antibacterial TargetChemogenetic analysis of human protein methyltransferasesCrystal Structures of Candida albicans Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal the Flexibility of Active Site Loop Residues Critical for Ligand Potency and Selectivity
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P1433
description
journal
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revista científica
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rivista scientifica
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vědecký časopis
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wetenschappelijk tijdschrift van Wiley-Blackwell
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wissenschaftliche Fachzeitschrift
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مجلة
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वैज्ञानिक पत्रिका
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英语期刊
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name
Chemical Biology & Drug Design
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Chemical Biology & Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology & Drug Design
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Chemical Biology & Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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prefLabel
Chemical Biology & Drug Design
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Chemical Biology & Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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Chemical Biology and Drug Design
@es
Chemical Biology and Drug Design
@fi
Chemical Biology and Drug Design
@fr
Chemical Biology and Drug Design
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Chemical Biology and Drug Design
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P1055
P1156
P236
P6981
P356
P4616
P1055
P1156
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Chemical Biology and Drug Design
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P236
P356
10.1111/(ISSN)1747-0285