Rac Regulates Its Effector Phospholipase C 2 through Interaction with a Split Pleckstrin Homology Domain
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Phosphoinositides: tiny lipids with giant impact on cell regulationRac-mediated Stimulation of Phospholipase Cγ2 Amplifies B Cell Receptor-induced Calcium Signaling.Structural basis for the Rho- and phosphoinositide-dependent localization of the exocyst subunit Sec3The phospholipase C isozymes and their regulationCompetition between Grb2 and Plcγ1 for FGFR2 regulates basal phospholipase activity and invasion.The Concise Guide to PHARMACOLOGY 2013/14: enzymes.Phospholipase C gamma 2 is critical for development of a murine model of inflammatory arthritis by affecting actin dynamics in dendritic cells.Mechanism of phosphorylation-induced activation of phospholipase C-gamma isozymes.Mechanism of activation and inactivation of Gq/phospholipase C-β signaling nodesCritical role of phospholipase Cgamma2 in integrin and Fc receptor-mediated neutrophil functions and the effector phase of autoimmune arthritis.Characterization of phospholipase C gamma enzymes with gain-of-function mutations.Pleckstrin homology (PH) like domains - versatile modules in protein-protein interaction platforms.Lipid and Protein Co-Regulation of PI3K Effectors Akt and Itk in Lymphocytes.Structures of Ras superfamily effector complexes: What have we learnt in two decades?Mechanism of Rac1-induced amplification in gastric mucosal phospholipase Cγ2 activation in response to Helicobacter pylori: modulatory effect of ghrelin.The 7-transmembrane protein homologue UL78 of the human cytomegalovirus forms oligomers and traffics between the plasma membrane and different intracellular compartments.Membrane environment exerts an important influence on rac-mediated activation of phospholipase Cγ2.Regulatory role of guanine nucleotide exchange factor (GEF) Dock180 phosphorylation on Tyr/Ser in mediation of gastric mucosal Rac1 activation in response to Helicobacter pylori and ghrelin.Chemokines and the signaling modules regulating integrin affinity.The Phospholipase Cγ2 Mutants R665W and L845F Identified in Ibrutinib-resistant Chronic Lymphocytic Leukemia Patients Are Hypersensitive to the Rho GTPase Rac2 Protein.Phospholipase C isozymes as effectors of Ras superfamily GTPases.A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine modelDynamic Allostery in PLCγ1 and Its Modulation by a Cancer Mutation Revealed by MD Simulation and NMRFunctional characterization of phospholipase C-γ mutant protein causing both somatic ibrutinib resistance and a germline monogenic autoinflammatory disorder
P2860
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P2860
Rac Regulates Its Effector Phospholipase C 2 through Interaction with a Split Pleckstrin Homology Domain
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Rac Regulates Its Effector Pho ...... lit Pleckstrin Homology Domain
@ast
Rac Regulates Its Effector Pho ...... lit Pleckstrin Homology Domain
@en
Rac Regulates Its Effector Pho ...... lit Pleckstrin Homology Domain
@nl
type
label
Rac Regulates Its Effector Pho ...... lit Pleckstrin Homology Domain
@ast
Rac Regulates Its Effector Pho ...... lit Pleckstrin Homology Domain
@en
Rac Regulates Its Effector Pho ...... lit Pleckstrin Homology Domain
@nl
prefLabel
Rac Regulates Its Effector Pho ...... lit Pleckstrin Homology Domain
@ast
Rac Regulates Its Effector Pho ...... lit Pleckstrin Homology Domain
@en
Rac Regulates Its Effector Pho ...... lit Pleckstrin Homology Domain
@nl
P2093
P2860
P356
P1476
rac regulates its effector pho ...... lit pleckstrin homology domain
@en
P2093
Claudia Walliser
Diego Esposito
Katy L Everett
Matilda Katan
Michael Retlich
Michelle B Josephs
Peter Gierschik
Petra Vatter
Richard Harris
Tom D Bunney
P2860
P304
30351-30362
P356
10.1074/JBC.M803316200
P407
P577
2008-08-26T00:00:00Z