Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1) - Test2 - elhamkhani - TriplyDB

Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

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Inhibition of human steroid 5beta-reductase (AKR1D1) by finasteride and structure of the enzyme-inhibitor complex Conversion of Human Steroid 5 -Reductase (AKR1D1) into 3 -Hydroxysteroid Dehydrogenase by Single Point Mutation E120H: EXAMPLE OF PERFECT ENZYME ENGINEERING Structures ofSaccharomyces cerevisiaeD-arabinose dehydrogenase Ara1 and its complex with NADPH: implications for cofactor-assisted substrate recognition Do androgens play a beneficial role in the regulation of vascular tone? Nongenomic vascular effects of testosterone metabolites.New frontiers in androgen biosynthesis and metabolism.Rate of steroid double-bond reduction catalysed by the human steroid 5β-reductase (AKR1D1) is sensitive to steroid structure: implications for steroid metabolism and bile acid synthesis The aldo-keto reductases (AKRs): Overview.Alternative splicing in the aldo-keto reductase superfamily: implications for protein nomenclature.5β-Reduced steroids and human Δ(4)-3-ketosteroid 5β-reductase (AKR1D1).Hypothesis on Serenoa repens (Bartram) small extract inhibition of prostatic 5α-reductase through an in silico approach on 5β-reductase x-ray structure.From alcohol dehydrogenase to a "one-way" carbonyl reductase by active-site redesign: a mechanistic study of mannitol 2-dehydrogenase from pseudomonas fluorescens.Aldo-keto reductases in which the conserved catalytic histidine is substituted

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P2860

Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

http://www.wikidata.org/entity/Q27652485

description

2009 nî lūn-bûn

@nan

2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

@ast

Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

@en

Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

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type

label

Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

@ast

Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

@en

Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

@nl

prefLabel

Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

@ast

Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

@en

Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

@nl

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J.MCE.2008.09.013

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Molecular and Cellular Endocrinology

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Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

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David W Christianson

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Jason E Drury

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Trevor M Penning

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P2860

Cloning and expression of cDNA of human delta 4-3-oxosteroid 5 beta-reductase and substrate specificity of the expressed enzyme

Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site

Crystal Structure of Human Liver 4-3-Ketosteroid 5 -Reductase (AKR1D1) and Implications for Substrate Binding and Catalysis

The crystal structure of human Delta4-3-ketosteroid 5beta-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism

Structure of 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase complexed with NADP+

Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase

The enzymes, regulation, and genetics of bile acid synthesis

Comparative anatomy of the aldo-keto reductase superfamily

Molecular cloning and sequence analysis of cDNA encoding delta 4-3-ketosteroid 5 beta-reductase of rat liver.

Purification and characterization of delta 4-3-ketosteroid 5 beta-reductase.

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191-8

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scholarly article

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10.1016/J.MCE.2008.09.013

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1-2

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301

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Luigi Di Costanzo

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2009-03-25T00:00:00Z

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23311850

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18848863

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2675190

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