Crystal Structures of Mycobacterium tuberculosis KasA Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin
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Structural and Functional Conservation of Mycobacterium tuberculosis GroEL Paralogs Suggests that GroEL1 Is a ChaperoninStructural Basis for the Recognition of Mycolic Acid Precursors by KasA, a Condensing Enzyme and Drug Target from Mycobacterium TuberculosisPhosphorylation of KasB regulates virulence and acid-fastness in Mycobacterium tuberculosisIdentification of KasA as the cellular target of an anti-tubercular scaffoldSlow onset inhibition of bacterial beta-ketoacyl-acyl carrier protein synthases by thiolactomycin.The polyketide backbone of thiolactomycin is assembled by an unusual iterative polyketide synthase.Structural Basis for the Regulation of the MmpL Transporters of Mycobacterium tuberculosis.Thiolactomycin-based β-ketoacyl-AcpM synthase A (KasA) inhibitors: fragment-based inhibitor discovery using transient one-dimensional nuclear overhauser effect NMR spectroscopy.Thiolactomycin-Based Inhibitors of Bacterial β-Ketoacyl-ACP Synthases with in Vivo Activity.Production of recombinant proteins in Mycobacterium smegmatis for structural and functional studies.Elucidation of the protonation states of the catalytic residues in mtKasA: implications for inhibitor design.Design, Synthesis and Biological Evaluation of Some Triazole Schiff's Base Derivatives as Potential Antitubercular Agents.Investigation of the anti-TB potential of selected propolis constituents using a molecular docking approachDie Fettsäuresynthese als Angriffspunkt
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P2860
Crystal Structures of Mycobacterium tuberculosis KasA Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Crystal Structures of Mycobact ...... s Inhibition by Thiolactomycin
@ast
Crystal Structures of Mycobact ...... s Inhibition by Thiolactomycin
@en
Crystal Structures of Mycobact ...... s Inhibition by Thiolactomycin
@nl
type
label
Crystal Structures of Mycobact ...... s Inhibition by Thiolactomycin
@ast
Crystal Structures of Mycobact ...... s Inhibition by Thiolactomycin
@en
Crystal Structures of Mycobact ...... s Inhibition by Thiolactomycin
@nl
prefLabel
Crystal Structures of Mycobact ...... s Inhibition by Thiolactomycin
@ast
Crystal Structures of Mycobact ...... s Inhibition by Thiolactomycin
@en
Crystal Structures of Mycobact ...... s Inhibition by Thiolactomycin
@nl
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Crystal Structures of Mycobact ...... s Inhibition by Thiolactomycin
@en
P2093
Carl A Machutta
Sylvia R Luckner
P2860
P304
P3181
P356
10.1016/J.STR.2009.04.012
P577
2009-07-15T00:00:00Z