Thiolactomycin-Based Inhibitors of Bacterial β-Ketoacyl-ACP Synthases with in Vivo Activity. - Test2 - elhamkhani - TriplyDB

Thiolactomycin-Based Inhibitors of Bacterial β-Ketoacyl-ACP Synthases with in Vivo Activity.

Thiolactomycin-Based Inhibitors of Bacterial β-Ketoacyl-ACP Synthases with in Vivo Activity.

http://www.wikidata.org/entity/Q37030173

about

Chemical probing of thiotetronate bio-assembly.The polyketide backbone of thiolactomycin is assembled by an unusual iterative polyketide synthase.A Facile Semi-Synthetic Approach towards Halogen-Substituted Aminobenzoic Acid Analogues of Platensimycin.Bacterial fatty acid metabolism in modern antibiotic discovery.Benzoxazoles, phthalazinones, and arylurea-based compounds with IMPDH-independent antibacterial activity against Francisella tularensis.Design, Synthesis and Biological Evaluation of Some Triazole Schiff's Base Derivatives as Potential Antitubercular Agents.An integrative, multi-omics approach towards the prioritization of Klebsiella pneumoniae drug targets.

P2860

Q36259328-6EE25CDC-8EC0-4FED-805F-31A358D47ECC Q36260641-78E1354F-7056-4744-81E3-FBC650EC1303 Q36408584-6BAD43F4-3C34-41AB-8C17-FFBC0065EDC6 Q38964523-5454D7D0-C644-4F27-A307-A9582591EC33 Q40121791-DD9AC7F6-AF8B-42A7-AC9C-0FC7B5A69BCF Q55286767-D6D349CB-17BA-4AC1-B30B-8CDD14B66659 Q55716547-72F5E1A2-699D-46B3-B674-8FD990925745

P2860

Thiolactomycin-Based Inhibitors of Bacterial β-Ketoacyl-ACP Synthases with in Vivo Activity.

http://www.wikidata.org/entity/Q37030173

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 17 May 2016

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Thiolactomycin-Based Inhibitor ...... nthases with in Vivo Activity.

@en

Thiolactomycin-Based Inhibitor ...... nthases with in Vivo Activity.

@nl

type

label

Thiolactomycin-Based Inhibitor ...... nthases with in Vivo Activity.

@en

Thiolactomycin-Based Inhibitor ...... nthases with in Vivo Activity.

@nl

prefLabel

Thiolactomycin-Based Inhibitor ...... nthases with in Vivo Activity.

@en

Thiolactomycin-Based Inhibitor ...... nthases with in Vivo Activity.

@nl

P1433

Q37030173-EF875694-1B6C-44C9-8A42-489AD968B6D2

P1476

Q37030173-FF8E24E1-AF0C-46E2-8DDF-9927183B4129

P2093

Q37030173-19307C41-6604-42F6-B52E-F8F386F76C26

Q37030173-2339C28C-9313-42FB-9BD5-8D4412C6322F

Q37030173-63096D05-F5B1-43F1-AB0B-DCCAA1652873

Q37030173-78639D15-9DFF-47EA-B894-5E18997634A6

Q37030173-AEE0C595-F8B6-4684-B6CE-6D0755A740F5

Q37030173-C9DC9D4C-96F3-4460-8F9C-1E9049B59D04

Q37030173-E8B63D04-ADD0-4ECB-997E-3E7B0D0FBD9B

P2860

Q37030173-006F8F8B-2B99-4E4A-890A-DA15CCED9DD8

Q37030173-03BE0950-587F-4335-B27C-55989A5B0FDA

Q37030173-1291730D-7A4F-423D-ABFB-B7F59C4A643B

Q37030173-165143BF-B94D-4165-A429-C3A5E083740F

Q37030173-186DFFAD-BABD-4C24-BF64-3588EC028CB1

Q37030173-19B59B39-08E5-4D88-9EC6-A27922C81533

Q37030173-1C79A0F3-DE7C-4F77-88E3-00603185C24F

Q37030173-1FB97871-9E28-49F0-B663-50DBDDFC8218

Q37030173-23D3EF4E-FAA6-444B-BF1E-F8102CF9D600

Q37030173-37502943-2F34-401A-9851-EC7DC67A179E

P304

Q37030173-FA9F7774-0676-4F95-90C2-9BC1DDF326A6

P31

Q37030173-CB1ABC84-2AB4-4EF7-A892-08B1222EEB11

P356

Q37030173-CAAAC72C-0752-430D-8F53-B697C006D084

P407

Q37030173-40011704-0391-4A6B-8111-390D6F1D55B9

P433

Q37030173-BE377AB1-2F51-4495-87F3-E3EDA268E7EF

P478

Q37030173-8F5F5059-E247-4946-AE0D-A585F9B1A73B

P50

Q37030173-D6A72BAA-1399-4715-8BEB-63733BD2A100

Q37030173-E24E3E9B-DF2B-412C-B4C9-9D9F181219D8

P577

Q37030173-CD9B6BF0-AAD4-4179-B045-71DD723A4903

P698

Q37030173-B6E7F53D-3EC8-4D9F-B423-81A03B72D84E

P932

Q37030173-C24E921F-7A3B-47BC-86DA-DB0ADEDCAB7B

P356

ACS.JMEDCHEM.6B00236

P1433

Journal of Medicinal Chemistry

P1476

Thiolactomycin-Based Inhibitor ...... nthases with in Vivo Activity.

@en

P2093

Chendi Gu

http://www.w3.org/2001/XMLSchema#string

Gopal R Bommineni

http://www.w3.org/2001/XMLSchema#string

Jason E Cummings

http://www.w3.org/2001/XMLSchema#string

Kanishk Kapilashrami

http://www.w3.org/2001/XMLSchema#string

Stephen G Walker

http://www.w3.org/2001/XMLSchema#string

Susan E Knudson

http://www.w3.org/2001/XMLSchema#string

Yang Lu

http://www.w3.org/2001/XMLSchema#string

P2860

Discovery of FabH/FabF inhibitors from natural products.

The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: adduct affinity and drug resistance

Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

Clarithromycin is an effective immunomodulator when administered late in experimental pyelonephritis by multidrug-resistant Pseudomonas aeruginosa.

The 1.8 A crystal structure and active-site architecture of beta-ketoacyl-acyl carrier protein synthase III (FabH) from escherichia coli

Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism

Crystal Structures of Mycobacterium tuberculosis KasA Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin

Structural Basis for the Recognition of Mycolic Acid Precursors by KasA, a Condensing Enzyme and Drug Target from Mycobacterium Tuberculosis

Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis

The Claisen condensation in biology

P304

5377-5390

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1021/ACS.JMEDCHEM.6B00236

http://www.w3.org/2001/XMLSchema#string

P407

P433

11

http://www.w3.org/2001/XMLSchema#string

P478

59

http://www.w3.org/2001/XMLSchema#string

P50

Richard Slayden

P577

2016-05-17T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

27187871

http://www.w3.org/2001/XMLSchema#string

P932

4917603

http://www.w3.org/2001/XMLSchema#string