Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration
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Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexinStructural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1Structural basis of semaphorin-plexin signallingStructure and function of the intracellular region of the plexin-b1 transmembrane receptorUnderstanding cell signalling systems: paving the way for new therapiesRegulation of small GTPases by GEFs, GAPs, and GDIsPlexins function in epithelial repair in both Drosophila and zebrafish.A Dual Binding Mode for RhoGTPases in Plexin SignallingNeuropilins lock secreted semaphorins onto plexins in a ternary signaling complexPlexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced DimerizationStructural basis for the prion-like MAVS filaments in antiviral innate immunitySelR reverses Mical-mediated oxidation of actin to regulate F-actin dynamics.F-actin dismantling through a redox-driven synergy between Mical and cofilin.Guidance receptor degradation is required for neuronal connectivity in the Drosophila nervous system.Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complexIdentification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium diseaseDiverse functions for the semaphorin receptor PlexinD1 in development and disease.Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.A cytosolic juxtamembrane interface modulates plexin A3 oligomerization and signal transduction.Structural basis of Rnd1 binding to plexin Rho GTPase binding domains (RBDs)Semaphorins in angiogenesis and tumor progression.Structural mechanisms of plexin signalingClass A Plexins Are Organized as Preformed Inactive Dimers on the Cell SurfaceSecondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEFInteraxonal interaction defines tiled presynaptic innervation in C. elegans.Emerging roles of Semaphorins in the regulation of epithelial and endothelial junctionsPlexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions.Class 3 semaphorins as a therapeutic target.Function of members of the neuropilin family as essential pleiotropic cell surface receptors.The role of the semaphorins in cancer.Regulating small G protein signaling to coordinate axon adhesion and repulsion.14-3-3ε couples protein kinase A to semaphorin signaling and silences plexin RasGAP-mediated axonal repulsion.Characterizing PKA-Mediated Phosphorylation of Plexin Using Purified Proteins.Cysteines in the neuropilin-2 MAM domain modulate receptor homooligomerization and signal transduction.Defective signaling through plexin-A1 compromises the development of the peripheral olfactory system and neuroendocrine reproductive axis in mice.Identification of target genes downstream of semaphorin6A/PlexinA2 signaling in zebrafish.In Vitro Assay for the Rap GTPase-Activating Protein Activity of the Purified Cytoplasmic Domain of Plexin.Isolated truncus arteriosus associated with a mutation in the plexin-D1 gene.Hologenomic adaptations underlying the evolution of sanguivory in the common vampire bat
P2860
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P2860
Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Crystal structure of the plexi ...... ough active site sequestration
@ast
Crystal structure of the plexi ...... ough active site sequestration
@en
Crystal structure of the plexi ...... ough active site sequestration
@nl
type
label
Crystal structure of the plexi ...... ough active site sequestration
@ast
Crystal structure of the plexi ...... ough active site sequestration
@en
Crystal structure of the plexi ...... ough active site sequestration
@nl
prefLabel
Crystal structure of the plexi ...... ough active site sequestration
@ast
Crystal structure of the plexi ...... ough active site sequestration
@en
Crystal structure of the plexi ...... ough active site sequestration
@nl
P2093
P2860
P921
P3181
P356
P1476
Crystal structure of the plexi ...... ough active site sequestration
@en
P2093
Jonathan R Terman
Taehong Yang
Xuewu Zhang
P2860
P304
P3181
P356
10.1073/PNAS.0906923106
P407
P577
2009-09-15T00:00:00Z