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Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexinEffect of cancer-associated mutations in the PlexinB1 geneUnderstanding cell signalling systems: paving the way for new therapiesRegulation of small GTPases by GEFs, GAPs, and GDIsModeling transmembrane domain dimers/trimers of plexin receptors: implications for mechanisms of signal transmission across the membraneNeuropilins lock secreted semaphorins onto plexins in a ternary signaling complexPlexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced DimerizationReverse Signaling by Semaphorin-6A Regulates Cellular Aggregation and Neuronal MorphologyStructure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complexA cytosolic juxtamembrane interface modulates plexin A3 oligomerization and signal transduction.The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling.Structural mechanisms of plexin signalingStructure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies.Class A Plexins Are Organized as Preformed Inactive Dimers on the Cell SurfaceSecondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEFEmerging roles of Semaphorins in the regulation of epithelial and endothelial junctionsPlexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions.Expression of recombinant glycoproteins in mammalian cells: towards an integrative approach to structural biology.Structures of Ras superfamily effector complexes: What have we learnt in two decades?Optogenetic activation of Plexin-B1 reveals contact repulsion between osteoclasts and osteoblasts.Molecular Dynamics Simulations Reveal Isoform Specific Contact Dynamics between the Plexin Rho GTPase Binding Domain (RBD) and Small Rho GTPases Rac1 and Rnd1.Regulating small G protein signaling to coordinate axon adhesion and repulsion.14-3-3ε couples protein kinase A to semaphorin signaling and silences plexin RasGAP-mediated axonal repulsion.Characterizing Plexin GTPase Interactions Using Gel Filtration, Surface Plasmon Resonance Spectrometry, and Isothermal Titration Calorimetry.Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation.Next generation sequencing in nonsyndromic intellectual disability: from a negative molecular karyotype to a possible causative mutation detection.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A Dual Binding Mode for RhoGTPases in Plexin Signalling
@ast
A Dual Binding Mode for RhoGTPases in Plexin Signalling
@en
A Dual Binding Mode for RhoGTPases in Plexin Signalling
@nl
type
label
A Dual Binding Mode for RhoGTPases in Plexin Signalling
@ast
A Dual Binding Mode for RhoGTPases in Plexin Signalling
@en
A Dual Binding Mode for RhoGTPases in Plexin Signalling
@nl
prefLabel
A Dual Binding Mode for RhoGTPases in Plexin Signalling
@ast
A Dual Binding Mode for RhoGTPases in Plexin Signalling
@en
A Dual Binding Mode for RhoGTPases in Plexin Signalling
@nl
P2093
P2860
P3181
P1433
P1476
A Dual Binding Mode for RhoGTPases in Plexin Signalling
@en
P2093
A Radu Aricescu
Christian H Bell
E Yvonne Jones
P2860
P304
P3181
P356
10.1371/JOURNAL.PBIO.1001134
P407
P577
2011-08-01T00:00:00Z