Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases

Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases

Item
http://www.wikidata.org/entity/Q27657523
In vivo protein crystallization opens new routes in structural biologyNatively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray LaserNonpeptidic Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors as Promising New Leads for Chagas Disease ChemotherapyComplementarity Between a Docking and a High-Throughput Screen in Discovering New Cruzain InhibitorsCrystal Structures of TbCatB and Rhodesain, Potential Chemotherapeutic Targets and Major Cysteine Proteases of Trypanosoma bruceiIn Vitro and In Vivo Studies of the Trypanocidal Properties of WRR-483 against Trypanosoma cruziSerial crystallography onin vivogrown microcrystals using synchrotron radiationThe Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases-Part III: In-Silico Molecular Docking InvestigationsNovel cruzain inhibitors for the treatment of Chagas' disease.Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1.Drug discovery for neglected tropical diseases at the Sandler Center.Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target.Reversible cysteine protease inhibitors show promise for a Chagas disease cure.Use of cysteine-reactive small molecules in drug discovery for trypanosomal disease.Dipeptidyl Enoates As Potent Rhodesain Inhibitors That Display a Dual Mode of Action.Tetrafluorophenoxymethyl ketone cruzain inhibitors with improved pharmacokinetic properties as therapeutic leads for Chagas' disease
P2860

Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases

Item
http://www.wikidata.org/entity/Q27657523
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Novel non-peptidic vinylsulfon ...... of parasite cysteine proteases
@ast
Novel non-peptidic vinylsulfon ...... of parasite cysteine proteases
@en
Novel non-peptidic vinylsulfon ...... of parasite cysteine proteases
@nl
type
label
Novel non-peptidic vinylsulfon ...... of parasite cysteine proteases
@ast
Novel non-peptidic vinylsulfon ...... of parasite cysteine proteases
@en
Novel non-peptidic vinylsulfon ...... of parasite cysteine proteases
@nl
prefLabel
Novel non-peptidic vinylsulfon ...... of parasite cysteine proteases
@ast
Novel non-peptidic vinylsulfon ...... of parasite cysteine proteases
@en
Novel non-peptidic vinylsulfon ...... of parasite cysteine proteases
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Novel non-peptidic vinylsulfon ...... of parasite cysteine proteases
@en
P2093
P2860
P304
P31
P356
10.1016/J.BMCL.2009.08.098
P407
P433
P478
P50
P577
P698
P921
P932