Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX
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Characterization of non-specific cytotoxic cell receptor protein 1: a new member of the lectin-type subfamily of F-box proteinsThermostable Carbonic Anhydrases in Biotechnological ApplicationsRecent developments in targeting carbonic anhydrase IX for cancer therapeuticsCoumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigationsHigh-Resolution Crystal Structure of the Subclass B3 Metallo- -Lactamase BJP-1: Rational Basis for Substrate Specificity and Interaction with SulfonamidesThe unique structure of carbonic anhydrase αCA1 from Chlamydomonas reinhardtiiDithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigationsDithiocarbamates Strongly Inhibit Carbonic Anhydrases and Show Antiglaucoma Action in VivoStructural and catalytic characterization of a thermally stable and acid-stable variant of human carbonic anhydrase II containing an engineered disulfide bondStructural elucidation of the hormonal inhibition mechanism of the bile acid cholate on human carbonic anhydrase IIX-ray structure of the first `extremo-α-carbonic anhydrase', a dimeric enzyme from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1The structural comparison between membrane-associated human carbonic anhydrases provides insights into drug design of selective inhibitorsCrystal structures of two tetrameric β-carbonic anhydrases from the filamentous ascomycete Sordaria macrosporaX-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitorThe Structure of Carbonic Anhydrase IX Is Adapted for Low-pH CatalysisPhenols and Polyphenols as Carbonic Anhydrase InhibitorsStructural and biophysical characterization of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2: insights into engineering thermostable enzymes for CO2 sequestrationThe tumour-associated carbonic anhydrases CA II, CA IX and CA XII in a group of medulloblastomas and supratentorial primitive neuroectodermal tumours: an association of CA IX with poor prognosis.Neutron structure of human carbonic anhydrase II in complex with methazolamide: mapping the solvent and hydrogen-bonding patterns of an effective clinical drug.Global transcriptional response to carbonic anhydrase IX deficiency in the mouse stomachCharacterization and inhibition studies of an α-carbonic anhydrase from the endangered sturgeon species Acipenser gueldenstaedti.Detecting extracellular carbonic anhydrase activity using membrane inlet mass spectrometry.Stabilization of anionic and neutral forms of a fluorophoric ligand at the active site of human carbonic anhydrase IRole of hypoxia and EGF on expression, activity, localization and phosphorylation of carbonic anhydrase IX in MDA-MB-231 breast cancer cells.In vivo imaging and quantification of carbonic anhydrase IX expression as an endogenous biomarker of tumor hypoxia.Catalysis and pH control by membrane-associated carbonic anhydrase IX in MDA-MB-231 breast cancer cellsSaccharin: a lead compound for structure-based drug design of carbonic anhydrase IX inhibitors.Role of zinc in catalytic activity of carbonic anhydrase IX.Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapyThe In Vitro and In Vivo Activity of the Microtubule Disruptor STX140 Is Mediated by Hif-1 Alpha and CAIX ExpressionA sucrose-binding site provides a lead towards an isoform-specific inhibitor of the cancer-associated enzyme carbonic anhydrase IX.Hit-Validation Methodologies for Ligands Isolated from DNA-Encoded Chemical Libraries.Carbon Dioxide "Trapped" in a β-Carbonic Anhydrase.Insights towards sulfonamide drug specificity in α-carbonic anhydrasesCarbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells.Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.DNA-linked Inhibitor Antibody Assay (DIANA) for sensitive and selective enzyme detection and inhibitor screening.Carbonic anhydrase inhibition with natural products: novel chemotypes and inhibition mechanisms.Carbonic anhydrase inhibitors and activators for novel therapeutic applications.Structure-based drug discovery of carbonic anhydrase inhibitors.
P2860
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P2860
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Crystal structure of the catal ...... ed human carbonic anhydrase IX
@ast
Crystal structure of the catal ...... ed human carbonic anhydrase IX
@en
Crystal structure of the catal ...... ed human carbonic anhydrase IX
@nl
type
label
Crystal structure of the catal ...... ed human carbonic anhydrase IX
@ast
Crystal structure of the catal ...... ed human carbonic anhydrase IX
@en
Crystal structure of the catal ...... ed human carbonic anhydrase IX
@nl
prefLabel
Crystal structure of the catal ...... ed human carbonic anhydrase IX
@ast
Crystal structure of the catal ...... ed human carbonic anhydrase IX
@en
Crystal structure of the catal ...... ed human carbonic anhydrase IX
@nl
P2093
P2860
P50
P356
P1476
Crystal structure of the catal ...... ed human carbonic anhydrase IX
@en
P2093
Carlo Pedone
Jaromir Pastorek
Peiwen Pan
Silvia Pastorekova
P2860
P304
P356
10.1073/PNAS.0908301106
P407
P50
P577
2009-09-22T00:00:00Z