New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights
about
Strength and specificity of the CMBA screening platform for bioactive molecules discoveryConnexin 30 expression inhibits growth of human malignant gliomas but protects them against radiation therapy.Structural basis of CX-4945 binding to human protein kinase CK2Flexibility of the P-loop of Pim-1 kinase: observation of a novel conformation induced by interaction with an inhibitorCrystal Structure of Pim1 Kinase in Complex with a Pyrido[4,3-D]Pyrimidine Derivative Suggests a Unique Binding ModeLow-density crystal packing of human protein kinase CK2 catalytic subunit in complex with resorufin or other ligands: a tool to study the unique hinge-region plasticity of the enzyme without packing biasStructural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potentialLarge scale meta-analysis of fragment-based screening campaigns: privileged fragments and complementary technologiesTargeting Pim kinases for cancer treatment: opportunities and challengesPIM1 kinase as a target for cancer therapyHigh-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors.Antitumoral activity of allosteric inhibitors of protein kinase CK2.[Small compounds libraries: a research tool for chemical biology].Tenfibgen-DMAT Nanocapsule Delivers CK2 Inhibitor DMAT to Prostate Cancer Xenograft Tumors Causing Inhibition of Cell Proliferation.Inhibition of Pim1 kinase activation attenuates allergen-induced airway hyperresponsiveness and inflammationStructural and functional determinants of protein kinase CK2α: facts and open questions.Revisiting protein kinase-substrate interactions: Toward therapeutic development.Exploring the prominent performance of CX-4945 derivatives as protein kinase CK2 inhibitors by a combined computational study.Phosphoproteome profile of human lung cancer cell line A549.Structural analysis of PIM1 kinase complexes with ATP-competitive inhibitors.Pharmacokinetic characterization of CK2 inhibitor CX-4945.
P2860
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P2860
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights
@ast
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights
@en
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights
@nl
type
label
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights
@ast
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights
@en
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights
@nl
prefLabel
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights
@ast
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights
@en
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights
@nl
P2093
P50
P356
P1433
P1476
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights
@en
P2093
Alex N Bullock
Céline F Sautel
David Grierson
Liliane Mouawad
Miriam López-Ramos
Renaud Prudent
Virginie Moucadel
P304
P356
10.1096/FJ.09-143743
P407
P50
P577
2010-04-16T00:00:00Z