Structural Basis for Assembly and Activation of the Heterotetrameric SAGA Histone H2B Deubiquitinase Module
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A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complexThe U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitinationThe structural plasticity of SCA7 domains defines their differential nucleosome-binding propertiesUbiquitin-specific peptidase 22 functions and its involvement in diseaseThe Importance of Ubiquitination and Deubiquitination in Cellular ReprogrammingA Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and ActivityThe crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicingUncovering the role of Sgf73 in maintaining SAGA deubiquitinating module structure and activity.Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes.A novel role for Sem1 and TREX-2 in transcription involves their impact on recruitment and H2B deubiquitylation activity of SAGA.Allosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1Poly(Q) Expansions in ATXN7 Affect Solubility but Not Activity of the SAGA Deubiquitinating ModulePulling complexes out of complex diseases: Spinocerebellar Ataxia 7.Sus1p facilitates pre-initiation complex formation at the SAGA-regulated genes independently of histone H2B de-ubiquitylationThe tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elementsThe SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription.The role of deubiquitinating enzymes in chromatin regulation.The Hog1 mitogen-activated protein kinase mediates a hypoxic response in Saccharomyces cerevisiae.SUS1 introns are required for efficient mRNA nuclear export in yeastConformational flexibility and subunit arrangement of the modular yeast Spt-Ada-Gcn5 acetyltransferase complexSplitting the task: Ubp8 and Ubp10 deubiquitinate different cellular pools of H2BK123.Phosphorylation of the deubiquitinase USP20 by protein kinase A regulates post-endocytic trafficking of β2 adrenergic receptors to autophagosomes during physiological stress.Transcriptome Profiling Identifies Multiplexin as a Target of SAGA Deubiquitinase Activity in Glia Required for Precise Axon Guidance During Drosophila Visual DevelopmentDrosophila models reveal novel insights into mechanisms underlying neurodegeneration.Sgf73, a subunit of SAGA complex, is required for the assembly of RITS complex in fission yeast.The ubiquitin-proteasome system of Saccharomyces cerevisiae.Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.The DUBm subunit Sgf11 is required for mRNA export and interacts with Cbp80 in DrosophilaA targeted in vivo RNAi screen reveals deubiquitinases as new regulators of Notch signaling.Cell-cycle perturbations suppress the slow-growth defect of spt10Δ mutants in Saccharomyces cerevisiae.Reversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells.Serine phosphorylation is critical for the activation of ubiquitin-specific protease 1 and its interaction with WD40-repeat protein UAF1.Structural basis for histone H2B deubiquitination by the SAGA DUB module.Sad1 counteracts Brr2-mediated dissociation of U4/U6.U5 in tri-snRNP homeostasis.Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration.DNA binding by Sgf11 protein affects histone H2B deubiquitination by Spt-Ada-Gcn5-acetyltransferase (SAGA).A new chapter in the transcription SAGA.Sus1/ENY2: a multitasking protein in eukaryotic gene expression.Deubiquitylases from genes to organism.
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P248
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P2860
Structural Basis for Assembly and Activation of the Heterotetrameric SAGA Histone H2B Deubiquitinase Module
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structural Basis for Assembly ...... tone H2B Deubiquitinase Module
@ast
Structural Basis for Assembly ...... tone H2B Deubiquitinase Module
@en
Structural Basis for Assembly ...... tone H2B Deubiquitinase Module
@nl
type
label
Structural Basis for Assembly ...... tone H2B Deubiquitinase Module
@ast
Structural Basis for Assembly ...... tone H2B Deubiquitinase Module
@en
Structural Basis for Assembly ...... tone H2B Deubiquitinase Module
@nl
prefLabel
Structural Basis for Assembly ...... tone H2B Deubiquitinase Module
@ast
Structural Basis for Assembly ...... tone H2B Deubiquitinase Module
@en
Structural Basis for Assembly ...... tone H2B Deubiquitinase Module
@nl
P2093
P2860
P3181
P1433
P1476
Structural Basis for Assembly ...... tone H2B Deubiquitinase Module
@en
P2093
Erik Zimmerman
Maren Schneider
Ning Zheng
P2860
P304
P3181
P356
10.1016/J.CELL.2010.04.026
P407
P577
2010-05-14T00:00:00Z