Structural analysis reveals the characteristic features of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillance
about
Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosomeAir2p is critical for the assembly and RNA-binding of the TRAMP complex and the KOW domain of Mtr4p is crucial for exosome activationRrp6: Integrated roles in nuclear RNA metabolism and transcription terminationThreading the barrel of the RNA exosomeSki2-like RNA helicase structures: common themes and complex assembliesRNA helicase proteins as chaperones and remodelersNuclear noncoding RNA surveillance: is the end in sight?Human Suv3 protein reveals unique features among SF2 helicasesThe crystal structure of S. cerevisiae Ski2, a DExH helicase associated with the cytoplasmic functions of the exosomeThe RNA helicase Mtr4p modulates polyadenylation in the TRAMP complex.The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein.RNA unwinding by the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complexThe RNA helicases AtMTR4 and HEN2 target specific subsets of nuclear transcripts for degradation by the nuclear exosome in Arabidopsis thalianaThe Sm complex is required for the processing of non-coding RNAs by the exosomeMutations in Mtr4 Structural Domains Reveal Their Important Role in Regulating tRNAiMet Turnover in Saccharomyces cerevisiae and Mtr4p Enzymatic Activities In Vitro.Structure of the frequency-interacting RNA helicase: a protein interaction hub for the circadian clock.Sen1 has unique structural features grafted on the architecture of the Upf1-like helicase familyComparison of the yeast and human nuclear exosome complexes.Winged helix domains with unknown function in Hel308 and related helicases.Emerging roles for ribonucleoprotein modification and remodeling in controlling RNA fateConserved RNA helicase FRH acts nonenzymatically to support the intrinsically disordered neurospora clock protein FRQ.Unique properties of the Mtr4p-poly(A) complex suggest a role in substrate targeting.GPKOW is essential for pre-mRNA splicing in vitro and suppresses splicing defect caused by dominant-negative DHX16 mutation in vivo.The Mtr4 ratchet helix and arch domain both function to promote RNA unwindingRoles of DEAD-box proteins in RNA and RNP Folding.An overview of pre-ribosomal RNA processing in eukaryotesMycobacterium smegmatis HelY Is an RNA-Activated ATPase/dATPase and 3'-to-5' Helicase That Unwinds 3'-Tailed RNA Duplexes and RNA:DNA Hybrids.Immature large ribosomal subunits containing the 7S pre-rRNA can engage in translation in Saccharomyces cerevisiaeNuclear RNA surveillance: role of TRAMP in controlling exosome specificity.Superfamily 2 helicasesMolecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila.An aromatic-rich loop couples DNA binding and ATP hydrolysis in the PriA DNA helicase.Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors.Yeast nuclear RNA processing.Rarely at rest: RNA helicases and their busy contributions to RNA degradation, regulation and quality control.Exosome substrate targeting: the long and short of it.The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase.The conformational plasticity of eukaryotic RNA-dependent ATPases.Functions and regulation of the Brr2 RNA helicase during splicing.Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA.
P2860
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P2860
Structural analysis reveals the characteristic features of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillance
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structural analysis reveals th ...... NA processing and surveillance
@ast
Structural analysis reveals th ...... NA processing and surveillance
@en
Structural analysis reveals th ...... NA processing and surveillance
@nl
type
label
Structural analysis reveals th ...... NA processing and surveillance
@ast
Structural analysis reveals th ...... NA processing and surveillance
@en
Structural analysis reveals th ...... NA processing and surveillance
@nl
prefLabel
Structural analysis reveals th ...... NA processing and surveillance
@ast
Structural analysis reveals th ...... NA processing and surveillance
@en
Structural analysis reveals th ...... NA processing and surveillance
@nl
P2093
P2860
P3181
P356
P1476
Structural analysis reveals th ...... NA processing and surveillance
@en
P2093
Fabien Bonneau
Jendrik Hentschel
John R Weir
P2860
P304
P3181
P356
10.1073/PNAS.1004953107
P407
P50
P577
2010-07-06T00:00:00Z