Biochemical and Structural Characterization of Bisubstrate Inhibitors of BasE, the Self-Standing Nonribosomal Peptide Synthetase Adenylate-Forming Enzyme of Acinetobactin Synthesis,
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Structural and Functional Investigation of the Intermolecular Interaction between NRPS Adenylation and Carrier Protein DomainsFunctional and Structural Analysis of the Siderophore Synthetase AsbB through Reconstitution of the Petrobactin Biosynthetic Pathway from Bacillus anthracisStructure of PA1221, a Nonribosomal Peptide Synthetase Containing Adenylation and Peptidyl Carrier Protein DomainsStructure determination of the functional domain interaction of a chimeric nonribosomal peptide synthetase from a challenging crystal with noncrystallographic translational symmetryEvolution of a pathogen: a comparative genomics analysis identifies a genetic pathway to pathogenesis in AcinetobacterBreaking a pathogen's iron will: Inhibiting siderophore production as an antimicrobial strategyDesigned Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosaTargeting iron assimilation to develop new antibacterials.Stable analogues of OSB-AMP: potent inhibitors of MenE, the o-succinylbenzoate-CoA synthetase from bacterial menaquinone biosynthesisInvestigation and conformational analysis of fluorinated nucleoside antibiotics targeting siderophore biosynthesis.Structural Biology of Nonribosomal Peptide SynthetasesNon-nucleoside inhibitors of BasE, an adenylating enzyme in the siderophore biosynthetic pathway of the opportunistic pathogen Acinetobacter baumannii.Synthesis of chromone, quinolone, and benzoxazinone sulfonamide nucleosides as conformationally constrained inhibitors of adenylating enzymes required for siderophore biosynthesis.Adenylating enzymes in Mycobacterium tuberculosis as drug targets.Structure and noncanonical chemistry of nonribosomal peptide biosynthetic machinery.Microbial siderophores: a mini review.Biochemical characterization and structural insight into aliphatic β-amino acid adenylation enzymes IdnL1 and CmiS6.The structural biology of biosynthetic megaenzymes.Structure of the adenylation domain Thr1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces sp. OH-5093-protein flexibility and molecular bases of substrate specificity.Nonribosomal peptide synthetase biosynthetic clusters of ESKAPE pathogens.Crystallization and preliminary X-ray crystallographic studies of VibE, a vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase from Vibrio cholerae.Prediction of the substrate for nonribosomal peptide synthetase (NRPS) adenylation domains by virtual screening.Post-translational Acetylation of MbtA Modulates Mycobacterial Siderophore Biosynthesis.Specific disulfide cross-linking to constrict the mobile carrier domain of nonribosomal peptide synthetases.The crystal structure of the adenylation enzyme VinN reveals a unique β-amino acid recognition mechanism.Design, synthesis, and biological evaluation of α-hydroxyacyl-AMS inhibitors of amino acid adenylation enzymes.PKS-NRPS Enzymology and Structural Biology: Considerations in Protein Production.Structure-function studies of acinetobactin analogs.In silico analysis of class I adenylate-forming enzymes reveals family and group-specific conservations
P2860
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P2860
Biochemical and Structural Characterization of Bisubstrate Inhibitors of BasE, the Self-Standing Nonribosomal Peptide Synthetase Adenylate-Forming Enzyme of Acinetobactin Synthesis,
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Biochemical and Structural Cha ...... me of Acinetobactin Synthesis,
@ast
Biochemical and Structural Cha ...... me of Acinetobactin Synthesis,
@en
Biochemical and Structural Cha ...... me of Acinetobactin Synthesis,
@nl
type
label
Biochemical and Structural Cha ...... me of Acinetobactin Synthesis,
@ast
Biochemical and Structural Cha ...... me of Acinetobactin Synthesis,
@en
Biochemical and Structural Cha ...... me of Acinetobactin Synthesis,
@nl
prefLabel
Biochemical and Structural Cha ...... me of Acinetobactin Synthesis,
@ast
Biochemical and Structural Cha ...... me of Acinetobactin Synthesis,
@en
Biochemical and Structural Cha ...... me of Acinetobactin Synthesis,
@nl
P2093
P2860
P356
P1433
P1476
Biochemical and structural cha ...... yme of acinetobactin synthesis
@en
P2093
Benjamin P Duckworth
Courtney C Aldrich
Eric J Drake
P2860
P304
P356
10.1021/BI101226N
P407
P577
2010-11-01T00:00:00Z