Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection - Test2 - elhamkhani - TriplyDB

Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection

Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection

http://www.wikidata.org/entity/Q27666863

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Human leukocyte Antigen-DM polymorphisms in autoimmune diseases Maturation and migration of murine CD4 single positive thymocytes and thymic emigrants Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4 Structure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicity Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop T-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex Interactions T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease T cells and their eons-old obsession with MHC A novel transport mechanism for MOMP in Chlamydophila pneumoniae and its putative role in immune-therapy MMDB and VAST+: tracking structural similarities between macromolecular complexes.A molecular view of multiple sclerosis and experimental autoimmune encephalitis: what can we learn from the epitope data?Identification of multiple public TCR repertoires in chronic beryllium disease.Design and Synthesis of Non-Peptide Mimetics Mapping the Immunodominant Myelin Basic Protein (MBP83-96) Epitope to Function as T-Cell Receptor Antagonists.Self-reactive human CD4 T cell clones form unusual immunological synapses Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide Identification of the Docking Site for CD3 on the T Cell Receptor β Chain by Solution NMR.HLA-DM constrains epitope selection in the human CD4 T cell response to vaccinia virus by favoring the presentation of peptides with longer HLA-DM-mediated half-lives Linkers in the structural biology of protein-protein interactions An NKp30-based chimeric antigen receptor promotes T cell effector functions and antitumor efficacy in vivo Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.Structural and biophysical insights into the role of CD4 and CD8 in T cell activation.Maturation and emigration of single-positive thymocytes.Recognition of self and altered self by T cells in autoimmunity and allergy.Structural and biophysical determinants of αβ T-cell antigen recognition.Self-tolerance in multiple sclerosis.Structural and dynamic control of T-cell receptor specificity, cross-reactivity, and binding mechanism.Structural basis for self-recognition by autoimmune T-cell receptors.Re-Directing CD4(+) T Cell Responses with the Flanking Residues of MHC Class II-Bound Peptides: The Core is Not Enough.The T cell antigen receptor: the Swiss army knife of the immune system.Thermal Stability of Heterotrimeric pMHC Proteins as Determined by Circular Dichroism Spectroscopy.Peptide profiling of Internet-obtained Cerebrolysin using high performance liquid chromatography - electrospray ionization ion trap and ultra high performance liquid chromatography - ion mobility - quadrupole time of flight mass spectrometry.Subtle changes in TCRα CDR1 profoundly increase the sensitivity of CD4 T cells Modification of the carboxy-terminal flanking region of a universal influenza epitope alters CD4⁺ T-cell repertoire selection The cytosolic domain of T-cell receptor ζ associates with membranes in a dynamic equilibrium and deeply penetrates the bilayer.HLA variation and disease.Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity

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P2860

Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection

http://www.wikidata.org/entity/Q27666863

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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Structure of a TCR with high a ...... escape from negative selection

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Structure of a TCR with high a ...... escape from negative selection

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Structure of a TCR with high a ...... escape from negative selection

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Structure of a TCR with high a ...... escape from negative selection

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Structure of a TCR with high a ...... escape from negative selection

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Structure of a TCR with high a ...... escape from negative selection

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Structure of a TCR with high a ...... escape from negative selection

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Structure of a TCR with high a ...... escape from negative selection

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P2860

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P1433

The EMBO Journal

P1476

Structure of a TCR with high a ...... escape from negative selection

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P2093

Melissa C Kerzic

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Roy A Mariuzza

http://www.w3.org/2001/XMLSchema#string

Yili Li

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P2860

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Structure of a complex of the human alpha/beta T cell receptor (TCR) HA1.7, influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRA*0101 and DRB1*0401): insight into TCR cross-restriction and alloreactiv

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Processing of X-ray diffraction data collected in oscillation mode

The crystal structure of a T cell receptor in complex with peptide and MHC class II

Crystal structure of a T cell receptor bound to an allogeneic MHC molecule

Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au

The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance

A structural basis for immunodominant human T cell receptor recognition

Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'

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1137-1148

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scholarly article

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1618340

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10.1038/EMBOJ.2011.21

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6

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30

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49813886

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21297580

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3061028

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