Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1 - Test2 - elhamkhani - TriplyDB

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1

http://www.wikidata.org/entity/Q27666866

about

Recombinant messenger RNA technology and its application in cancer immunotherapy, transcript replacement therapies, pluripotent stem cell induction, and beyond Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases Dxo1 is a new type of eukaryotic enzyme with both decapping and 5′-3′ exoribonuclease activity Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease XRN1 stalling in the 5' UTR of Hepatitis C virus and Bovine Viral Diarrhea virus is associated with dysregulated host mRNA stability XRN1 Is a Species-Specific Virus Restriction Factor in Yeasts Structured RNAs that evade or confound exonucleases: function follows form.A noncoding RNA produced by arthropod-borne flaviviruses inhibits the cellular exoribonuclease XRN1 and alters host mRNA stability Strategies for viral RNA stability: live long and prosper Neutralizing mutations of carboxylates that bind metal 2 in T5 flap endonuclease result in an enzyme that still requires two metal ions Restriction-based Multiple-fragment Assembly Strategy to Avoid Random Mutation during Long cDNA Cloning.A Novel Epigenetic Silencing Pathway Involving the Highly Conserved 5'-3' Exoribonuclease Dhp1/Rat1/Xrn2 in Schizosaccharomyces pombe.Flap endonucleases pass 5'-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5'-ends.P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates.RNA-seq reveals post-transcriptional regulation of Drosophila insulin-like peptide dilp8 and the neuropeptide-like precursor Nplp2 by the exoribonuclease Pacman/XRN1.Standing your ground to exoribonucleases: Function of Flavivirus long non-coding RNAs.Interaction of host cell microRNAs with the HCV RNA genome during infection of liver cells.Structural basis and function of XRN2 binding by XTB domains RNA structures that resist degradation by Xrn1 produce a pathogenic Dengue virus RNA The 5' → 3' exoribonuclease XRN1/Pacman and its functions in cellular processes and development.Inhibition and avoidance of mRNA degradation by RNA viruses.RNA degradation in Saccharomyces cerevisae The role of disordered protein regions in the assembly of decapping complexes and RNP granules.Interrelations between translation and general mRNA degradation in yeast.The activation of the decapping enzyme DCP2 by DCP1 occurs on the EDC4 scaffold and involves a conserved loop in DCP1.KSHV SOX mediated host shutoff: the molecular mechanism underlying mRNA transcript processing.Comparison of preribosomal RNA processing pathways in yeast, plant and human cells - focus on coordinated action of endo- and exoribonucleases.Degradation of initiator tRNAMet by Xrn1/2 via its accumulation in the nucleus of heat-treated HeLa cells.Simple and inexpensive three-step rapid amplification of cDNA 5' ends using 5' phosphorylated primers.In vitro labeling strategies for in cellulo fluorescence microscopy of single ribonucleoprotein machines.The yeast rapid tRNA decay pathway primarily monitors the structural integrity of the acceptor and T-stems of mature tRNA.Identification of phlebovirus and arenavirus RNA sequences that stall and repress the exoribonuclease XRN1.Mechanism and structural diversity of exoribonuclease-resistant RNA structures in flaviviral RNAs.Structural mechanism of DNA interstrand cross-link unhooking by the bacterial FAN1 nuclease.Beet Necrotic Yellow Vein Virus Noncoding RNA Production Depends on a 5'→3' Xrn Exoribonuclease Activity.A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure

P2860

Q26861563-65B3FB08-A2FD-4344-940B-A57FDE02B375 Q27005670-5631F02B-0089-4FDC-9234-80DA527FC546 Q27672794-B686926A-C3FD-4994-A554-112499B6F01F Q27727694-6362396E-65AE-41F6-9C62-997DE099342B Q27883674-26D7B578-E071-44BD-AEAC-6AF26B23BAF7 Q28543912-7FAE538E-A875-445A-8849-A045A22EC652 Q28554545-5C5B9E28-26BA-4F81-8D9D-E086312577B6 Q33552854-9A2D303B-7579-4DCC-B157-A71B00533106 Q34301595-B18104E1-BAD1-4540-A4C5-641787BDD1CE Q35069751-8620CEB3-F6AA-44F8-831A-DAB206ABC626 Q35183008-A0B3D31B-AEB3-47FE-BC2F-FA7FFF365C95 Q35664754-7C36AF49-4BF2-44DE-8491-4B01FCF24C4F Q35927018-499848B5-2DB1-403B-8371-F25EF4491512 Q36044859-C5B8605B-2826-4B4B-BC2D-FF29C8ECBA52 Q36432038-7F426816-B50A-4361-B937-CCDBAA1789E9 Q36443304-DA9667A5-85DF-4B4A-B9E2-EAFAF9732667 Q36553913-EE6FE224-2145-4724-90C7-387473CE682E Q36801398-C62E9FB1-B200-4FE9-8F64-B799CD59E715 Q36956243-23D7DAB7-611B-4514-9860-17DD4E402E62 Q37670700-C29223B8-0135-4A62-842D-2DE1DF7DB99A Q37989882-7EE12915-2B8D-4AD5-9291-DAAB8CE5E6DF Q38012919-0F65ED27-0B9B-4D3E-95A0-470D918E504D Q38025564-287ACF8C-1068-4565-A680-B66A429558AF Q38172402-853CB992-B707-4D56-ACD6-DCC4C475F4BE Q38221467-FC09A536-9373-4F32-A421-CB9DBDFB5551 Q39095308-824C528A-CCF1-4E2D-BD98-0F6AEE5708D0 Q39166342-97C4A1ED-4B7C-4C73-ADA0-C0A9EF64917B Q39317738-B815FFED-D662-4615-B28D-35EC50FC0D73 Q39987352-C6DA9AAF-CA0A-4CBD-967E-97BFEAEB88CA Q40269307-0666FF06-F506-4924-A72E-BE94C1111C46 Q40405192-D03D4F05-59E3-4161-B466-688C8F509487 Q41959880-675D1D09-BF10-4975-9C88-FCE278F4C1E9 Q43046605-A2BFBED7-563A-4E9C-BE77-8705C29ED2BD Q47215571-9FE6880F-9B19-42F3-94EB-11DD3DE000B6 Q52689255-A754F61E-1B64-4FE5-B581-D7B30E7C2FD6 Q54251634-9A2E4A53-5A48-4E78-B791-525E27CA11E4 Q57753832-D0836981-0E71-40E3-B47F-E43945F28F72

P2860

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1

http://www.wikidata.org/entity/Q27666866

description

2011 nî lūn-bûn

@nan

2011 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մարտին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1

@ast

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1

@en

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1

@nl

type

label

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1

@ast

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1

@en

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1

@nl

prefLabel

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1

@ast

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1

@en

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1

@nl

P1433

Q27666866-5C726CD5-D9CD-4E45-9516-6517039B63FC

P1476

Q27666866-A073FDF6-BFC3-43E8-93E5-51DC49DD9D4F

P2093

Q27666866-32EFDE84-F532-411C-92F5-FE09958F302B

Q27666866-A8766B9E-3C5C-48B7-A7EA-2B6523E334BC

P2860

Q27666866-007BCA50-0947-4A5C-AD5D-F292DBD4878C

Q27666866-04E5605B-8A0B-4DD8-B436-350C09774F06

Q27666866-0C6B32AC-67DC-4037-9CB7-5BA3937C41CD

Q27666866-0F638AA1-CE5A-4897-8AD1-8CD38F4DE7D3

Q27666866-17B7FD0F-51FE-408F-804D-CE6545ADF129

Q27666866-22FCC7E7-A12A-47B2-B0B1-EC8D80D33EFD

Q27666866-24443D11-83C0-461F-A07C-E0E04EAF3CF8

Q27666866-26613510-6F7C-45FB-8CEE-E51BF8EB5E70

Q27666866-2773DE32-9F2D-432B-9577-28595E7F24B4

Q27666866-2B5B97C1-6FD7-4E3B-9466-C6BB5112AF34

P2888

Q27666866-0CE3B014-2BC1-48A0-AB16-537AAAB2FBF3

P304

Q27666866-79A83650-2EB6-4FD2-A04B-6094085B7CF8

P31

Q27666866-2287773D-5B74-46CB-A947-925740554D95

P3181

Q27666866-4DDCA7EB-396C-4AF9-AACF-D6F059373240

P356

Q27666866-834EF9BD-B795-4B31-9DB0-8EC4E1C9F232

P433

Q27666866-EC7066E2-F0E1-4A11-B4C3-F3E9651A22E2

P478

Q27666866-27F3B049-3520-4515-9E48-54798F2B9B6A

P50

Q27666866-282B334E-FFE6-48DF-BC55-134CB4991503

Q27666866-87777C75-368C-4F87-BDE4-4EECCA7F885D

Q27666866-C67974BE-8F0D-4D62-A1DA-2D37598007F1

P577

Q27666866-4DDE3F0D-5D99-49F0-B31C-2ACB8BE1106A

P5875

Q27666866-1DF8B238-2D29-4F99-A24E-8AD8DFFA96D9

P6179

Q27666866-6BF3C417-E27A-45C1-829A-D656F5D8F04E

P698

Q27666866-8F60B725-5E2A-4C27-8E65-A1D07A282467

P921

Q27666866-AD76895A-DE0C-4320-8153-A354E88A0468

P932

Q27666866-3D66F3FE-E91D-4F45-9119-4C610787D760

P3181

P356

P1433

Nature Structural & Molecular Biology

P1476

Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1

@en

P2093

Jeong Ho Chang

http://www.w3.org/2001/XMLSchema#string

Kehui Xiang

http://www.w3.org/2001/XMLSchema#string

P2860

The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53

Human 5' --> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites

Efficient termination of transcription by RNA polymerase I requires the 5' exonuclease Rat1 in yeast

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription termination

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Processing of X-ray diffraction data collected in oscillation mode

Crystal structures of transcription factor NusG in light of its nucleic acid- and protein-binding activities

Structural Basis for the Recognition of Methylated Histone H3K36 by the Eaf3 Subunit of Histone Deacetylase Complex Rpd3S

P2888

P304

270-6

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

3114431

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NSMB.1984

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

18

http://www.w3.org/2001/XMLSchema#string

P50

James L. Manley

P577

2011-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49813940

http://www.w3.org/2001/XMLSchema#string

P6179

1029685496

http://www.w3.org/2001/XMLSchema#string

P698

21297639

http://www.w3.org/2001/XMLSchema#string

P921

structural biology

P932

3075561

http://www.w3.org/2001/XMLSchema#string