Utilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia pestis Outer Protein H (YopH) Phosphatase ‡
about
Small molecule tools for functional interrogation of protein tyrosine phosphatasesStructure of the Trypanosoma cruzi protein tyrosine phosphatase TcPTP1, a potential therapeutic target for Chagas’ diseaseStructure-guided studies of the SHP-1/JAK1 interaction provide new insights into phosphatase catalytic domain substrate recognitionOxime-based click chemistry in the development of 3-isoxazolecarboxylic acid containing inhibitors of Yersinia pestis protein tyrosine phosphatase, YopH.Oxime-based linker libraries as a general approach for the rapid generation and screening of multidentate inhibitors.Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase.Biomolecular Interactions of small-molecule inhibitors affecting the YopH protein tyrosine phosphatase.Integrating virtual and biochemical screening for protein tyrosine phosphatase inhibitor discovery.Structural analysis of human dual-specificity phosphatase 22 complexed with a phosphotyrosine-like substrate.Structure of human dual-specificity phosphatase 7, a potential cancer drug target.Inhibitors of the Yersinia protein tyrosine phosphatase through high throughput and virtual screening approaches.Protein tyrosine phosphatase structure-function relationships in regulation and pathogenesis.Druggability analysis and classification of protein tyrosine phosphatase active sites.X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors.New Prospects toward the Synthesis of Difluoromethylated Phosphate Mimics.Copper-Mediated Introduction of the CF2 PO(OEt)2 Motif: Scope and Limitations.TS-Chemscore, a Target-Specific Scoring Function, Significantly Improves the Performance of Scoring in Virtual Screening.Electrochemical behavior of N -oxyphthalimides: Cascades initiating self-sustaining catalytic reductive N ―O bond cleavageOxidative CO Cross-Coupling of 1,3-Dicarbonyl Compounds and Their Heteroanalogues withN-Substituted Hydroxamic Acids andN-Hydroxyimides
P2860
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P2860
Utilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia pestis Outer Protein H (YopH) Phosphatase ‡
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
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2011年論文
@zh-hk
2011年論文
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2011年論文
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2011年论文
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name
Utilization of Nitrophenylphos ...... Protein H (YopH) Phosphatase ‡
@ast
Utilization of Nitrophenylphos ...... Protein H (YopH) Phosphatase ‡
@en
Utilization of Nitrophenylphos ...... Protein H (YopH) Phosphatase ‡
@nl
type
label
Utilization of Nitrophenylphos ...... Protein H (YopH) Phosphatase ‡
@ast
Utilization of Nitrophenylphos ...... Protein H (YopH) Phosphatase ‡
@en
Utilization of Nitrophenylphos ...... Protein H (YopH) Phosphatase ‡
@nl
prefLabel
Utilization of Nitrophenylphos ...... Protein H (YopH) Phosphatase ‡
@ast
Utilization of Nitrophenylphos ...... Protein H (YopH) Phosphatase ‡
@en
Utilization of Nitrophenylphos ...... Protein H (YopH) Phosphatase ‡
@nl
P2093
P2860
P3181
P356
P1476
Utilization of Nitrophenylphos ...... Protein H (YopH) Phosphatase ‡
@en
P2093
Beverly Dyas
David S Waugh
George T Lountos
Medhanit Bahta
Robert G Ulrich
Sung-Eun Kim
Terrence R Burke
P2860
P304
P3181
P356
10.1021/JM200022G
P407
P577
2011-04-28T00:00:00Z