Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic β-Sheet Mimics
about
Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicityOut-of-register -sheets suggest a pathway to toxic amyloid aggregatesAtomic View of a Toxic Amyloid Small OligomerCrystal Structure of a Human Prion Protein Fragment Reveals a Motif for Oligomer FormationX-ray Crystallographic Structures of Trimers and Higher-Order Oligomeric Assemblies of a Peptide Derived from Aβ 17–36A Fibril-Like Assembly of Oligomers of a Peptide Derived from β-AmyloidAn Atomistic View of Amyloidogenic Self-assembly: Structure and Dynamics of Heterogeneous Conformational States in the Pre-nucleation Phase.Toxic fibrillar oligomers of amyloid-β have cross-β structure.The OPEP protein model: from single molecules, amyloid formation, crowding and hydrodynamics to DNA/RNA systemsA Newcomer's Guide to Peptide CrystallographyHeterodivalent linked macrocyclic β-sheets with enhanced activity against Aβ aggregation: two sites are better than one.The zipper groups of the amyloid state of proteins.X-ray Crystallographic Structure of Oligomers Formed by a Toxic β-Hairpin Derived from α-Synuclein: Trimers and Higher-Order Oligomers.The supramolecular chemistry of β-sheets.Structural insights into Aβ42 oligomers using site-directed spin labelingCrystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.Structures of oligomers of a peptide from β-amyloid.Square channels formed by a peptide derived from transthyretinPolymorphism of oligomers of a peptide from β-amyloid.Observation of molecular inhibition and binding structures of amyloid peptides.Misfolding of amyloidogenic proteins and their interactions with membranes.Chemical Methods to Knock Down the Amyloid Proteins.Detection of Aβ Monomers and Oligomers: Early Diagnosis of Alzheimer's Disease.Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology.Parallel β-sheet secondary structure is stabilized and terminated by interstrand disulfide cross-linkingSomatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers.Stages and conformations of the Tau repeat domain during aggregation and its effect on neuronal toxicityImpact of strand length on the stability of parallel-β-sheet secondary structure.New charge-bearing amino acid residues that promote β-sheet secondary structure.Spontaneous head-to-tail cyclization of unprotected linear peptides with the KAHA ligation.Inhibiting and reversing amyloid-β peptide (1-40) fibril formation with gramicidin S and engineered analogues.Amyloid β-Derived Diffusible Ligands (ADDLs) Induce Abnormal Autophagy Associated with Aβ Aggregation Degree.The Unexpected Role of Aβ1-42 Monomers in the Pathogenesis of Alzheimer's Disease.Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations.Structural features and molecular aggregations of designed triple-stranded β-sheets in single crystals.Analysis of designed β-hairpin peptides: molecular conformation and packing in crystals.Clearance of the intracellular high level of the tau protein directed by an artificial synthetic hydrolase.Elucidating the Structures of Amyloid Oligomers with Macrocyclic β-Hairpin Peptides: Insights into Alzheimer's Disease and Other Amyloid Diseases.Structural, thermodynamical, and dynamical properties of oligomers formed by the amyloid NNQQ peptide: Insights from coarse-grained simulationsCyclic Peptides as Inhibitors of Amyloid Fibrillation
P2860
Q27674676-73A25CEB-323A-4FE5-930A-0EFA63B63C8BQ27675366-74E36113-5E08-4773-81B3-2F0356B089D9Q27677948-104529B3-BB93-4DB5-823B-A0F0ADE8A944Q27678836-1F3A36DF-BDDA-4DD3-841E-E9A11A58419DQ27682495-9BAB2A8B-0A8E-41C1-8B28-10EF94DDC075Q27684839-9DA2EB83-CE00-45FD-8109-333C56DF51F8Q30152729-5F6210DD-DED7-4EEF-9F5A-15831A449298Q30514124-B316CAF3-418F-4909-92A3-20B514A7D615Q35590418-FE22A075-1410-4B82-A4EE-68AC240CB33FQ35869835-14F3FEF6-B7CB-404A-903C-E9974D686F0CQ36198736-8A685A9B-D904-49F4-9C8D-0DF8DF74E839Q36709769-250E238C-6459-4577-B73E-AE497FCABCF7Q36781124-58E05FB7-05FD-496E-84BC-1061712B6ACAQ36811839-89CC3A33-C129-4A2B-81B1-E9DDABFA0ECDQ36967253-AA5B2017-B98D-42FB-8FDB-014EF0EA5FEDQ37075263-BB303338-C11D-4BBB-95DD-EE9C54C29C17Q37207738-8EF8E3C7-11F1-41DE-B3BF-3DB9142A7124Q37707886-E5ABF6B4-3C9D-48AC-9DB5-949EC18399D9Q37731524-46DC1A07-B568-4C49-A1CF-50DBB738D9F2Q37984010-20D6A6F6-AF0D-461F-8FD2-16312600698CQ38223686-3994555D-4DC5-428F-BC19-40E81282DBB1Q38740479-2605FC34-9EB3-42C8-9417-A5767D0BB3F1Q38781556-350244C8-416A-46F9-AB66-9A498701EF8DQ39322110-76A927D7-A4FC-4D58-A29F-E3B1795779F0Q40657156-C042EE26-9EDD-4F45-A0B4-915E5A0EC9A3Q40984233-A7015E6A-CF6F-472D-9ED0-12725C9E6130Q41984715-87914C56-0D53-46DD-9BAA-36D9A364D254Q42076127-66434463-2C39-4517-93DA-921886C6FE17Q42552723-8C6055B4-CD60-4D4B-9DBB-12587C216B8EQ44494125-5A59E105-39C4-4A8C-81F4-28C02E46547EQ46864842-0A32C9A3-16D7-47EA-BCED-364D75EB63BBQ47272029-E95026F9-EF1C-4A46-B8CB-60BDB0466255Q47441295-F4FC21CE-02D0-4CC7-A324-7C6E80054D68Q49907306-2B04BBDA-48F9-4080-8B8E-7E2EF6373674Q50869555-F94C7218-B17E-4721-937F-35FD452F5B4BQ50988137-DBF52571-CF17-4DF4-B055-88EC5E1AF6B3Q51043710-1D7D2314-10B6-48D6-BB49-8DCD8B2AAB81Q52672253-3578EEF8-F2C8-4831-84FB-0373EADF67F6Q57840256-A8C8FF86-C982-48CB-83C0-6E6666A96429Q58097957-92C4F260-CB81-4FFC-8B35-1BCFD6B82957
P2860
Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic β-Sheet Mimics
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Characteristics of Amyloid-Rel ...... of Macrocyclic β-Sheet Mimics
@ast
Characteristics of Amyloid-Rel ...... of Macrocyclic β-Sheet Mimics
@en
Characteristics of Amyloid-Rel ...... of Macrocyclic β-Sheet Mimics
@nl
type
label
Characteristics of Amyloid-Rel ...... of Macrocyclic β-Sheet Mimics
@ast
Characteristics of Amyloid-Rel ...... of Macrocyclic β-Sheet Mimics
@en
Characteristics of Amyloid-Rel ...... of Macrocyclic β-Sheet Mimics
@nl
prefLabel
Characteristics of Amyloid-Rel ...... of Macrocyclic β-Sheet Mimics
@ast
Characteristics of Amyloid-Rel ...... of Macrocyclic β-Sheet Mimics
@en
Characteristics of Amyloid-Rel ...... of Macrocyclic β-Sheet Mimics
@nl
P2093
P2860
P3181
P356
P1476
Characteristics of Amyloid-Rel ...... of Macrocyclic β-Sheet Mimics
@en
P2093
James S Nowick
Jing Zheng
Pin-Nan Cheng
P2860
P304
P3181
P356
10.1021/JA200222N
P407
P577
2011-05-04T00:00:00Z