Stabilization of a -hairpin in monomeric Alzheimer's amyloid- peptide inhibits amyloid formation - Test2 - elhamkhani - TriplyDB

Stabilization of a -hairpin in monomeric Alzheimer's amyloid- peptide inhibits amyloid formation

Stabilization of a -hairpin in monomeric Alzheimer's amyloid- peptide inhibits amyloid formation

http://www.wikidata.org/entity/Q27650192

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β-hairpin-mediated formation of structurally distinct multimers of neurotoxic prion peptides Human serum albumin inhibits Abeta fibrillization through a "monomer-competitor" mechanism Alzheimer's disease--a panorama glimpse Structures of Aβ-Related Peptide−Monoclonal Antibody Complexes ,Minimalist design of water-soluble cross-beta architecture.Structural basis for high-affinity HER2 receptor binding by an engineered protein Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic β-Sheet Mimics X-ray Crystallographic Structures of Trimers and Higher-Order Oligomeric Assemblies of a Peptide Derived from Aβ 17–36 Crystal structure reveals conservation of amyloid-β conformation recognized by 3D6 following humanization to bapineuzumab A Fibril-Like Assembly of Oligomers of a Peptide Derived from β-Amyloid Sequestration of a β-hairpin for control of α-synuclein aggregation Nanobodies and recombinant binders in cell biology NMR structure of the water soluble Aβ17-34 peptide Influence of preformed Asp23-Lys28 salt bridge on the conformational fluctuations of monomers and dimers of Abeta peptides with implications for rates of fibril formation Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo Interaction between amyloid beta peptide and an aggregation blocker peptide mimicking islet amyloid polypeptide A foldamer-dendrimer conjugate neutralizes synaptotoxic β-amyloid oligomers Common features at the start of the neurodegeneration cascade Amyloid-β protofibrils: size, morphology and synaptotoxicity of an engineered mimic Fibrils of Truncated Pyroglutamyl-Modified Aβ Peptide Exhibit a Similar Structure as Wildtype Mature Aβ Fibrils Antiparallel triple-strand architecture for prefibrillar Aβ42 oligomers Aggregation and fibril morphology of the Arctic mutation of Alzheimer's Aβ peptide by CD, TEM, STEM and in situ AFM Toxic fibrillar oligomers of amyloid-β have cross-β structure.Mapping the interactions between the Alzheimer's Aβ-peptide and human serum albumin beyond domain resolution.Nano-assembly of amyloid β peptide: role of the hairpin fold.Associating a negatively charged GdDOTA-derivative to the Pittsburgh compound B for targeting Aβ amyloid aggregates.Alternative binding proteins: affibody binding proteins developed from a small three-helix bundle scaffold.Recombinant amyloid beta-peptide production by coexpression with an affibody ligand.Amyloidogenic regions and interaction surfaces overlap in globular proteins related to conformational diseases.Structural Changes of Amyloid Beta in Hippocampus of Rats Exposed to Ozone: A Raman Spectroscopy Study.Transient formation of intermediate conformational states of amyloid-β peptide revealed by heteronuclear magnetic resonance spectroscopy.Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies.Stabilization of neurotoxic Alzheimer amyloid-beta oligomers by protein engineering Fibril elongation by Aβ(17-42): kinetic network analysis of hybrid-resolution molecular dynamics simulations Mechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane.Structural insights for engineering binding proteins based on non-antibody scaffolds Dominance of misfolded intermediates in the dynamics of α-helix folding Staphylococcal display for combinatorial protein engineering of a head-to-tail affibody dimer binding the Alzheimer amyloid-β peptide.Multiplex epitope mapping using bacterial surface display reveals both linear and conformational epitopes.Structural basis of IL-23 antagonism by an Alphabody protein scaffold

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P2860

Stabilization of a -hairpin in monomeric Alzheimer's amyloid- peptide inhibits amyloid formation

http://www.wikidata.org/entity/Q27650192

description

2008 nî lūn-bûn

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2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2008 թվականի ապրիլին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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Stabilization of a -hairpin i ...... ide inhibits amyloid formation

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Stabilization of a -hairpin i ...... ide inhibits amyloid formation

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Stabilization of a -hairpin i ...... ide inhibits amyloid formation

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type

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Stabilization of a -hairpin i ...... ide inhibits amyloid formation

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Stabilization of a -hairpin i ...... ide inhibits amyloid formation

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Stabilization of a -hairpin i ...... ide inhibits amyloid formation

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prefLabel

Stabilization of a -hairpin i ...... ide inhibits amyloid formation

@ast

Stabilization of a -hairpin i ...... ide inhibits amyloid formation

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Stabilization of a -hairpin i ...... ide inhibits amyloid formation

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PNAS.0711731105

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Proceedings of the National Academy of Sciences of the United States of America

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Stabilization of a -hairpin i ...... ide inhibits amyloid formation

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Andreas Jonsson

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P2860

An affibody in complex with a target protein: Structure and coupled folding

Molecular basis for passive immunotherapy of Alzheimer's disease

Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution

The Xplor-NIH NMR molecular structure determination package

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Protein backbone angle restraints from searching a database for chemical shift and sequence homology

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

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5099-104

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scholarly article

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3429424

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10.1073/PNAS.0711731105

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13

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105

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Caroline Grönwall

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5476352

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18375754

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Alzheimer's disease

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2278213

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