Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex
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The footprint of genome architecture in the largest genome expansion in RNA virusesmRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral ResearchBiochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein ComplexNonstructural Proteins 7 and 8 of Feline Coronavirus Form a 2:1 Heterotrimer That Exhibits Primer-Independent RNA Polymerase ActivityCoronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Reduce Replication and PathogenesisCoronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes.Coronaviruses: an overview of their replication and pathogenesis.X-ray structure and activities of an essential Mononegavirales L-protein domainCoronavirus non-structural protein 16: evasion, attenuation, and possible treatments.Mutations in coronavirus nonstructural protein 10 decrease virus replication fidelityStructural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complexPurification, crystallization and preliminary X-ray analysis of nonstructural protein 2 (nsp2) from avian infectious bronchitis virus.RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex.Severe acute respiratory syndrome coronavirus nsp1 facilitates efficient propagation in cells through a specific translational shutoff of host mRNA.Critical Role of K1685 and K1829 in the Large Protein of Rabies Virus in Viral Pathogenicity and Immune EvasionExtensive Positive Selection Drives the Evolution of Nonstructural Proteins in Lineage C Betacoronaviruses.In Situ Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins.Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions.Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity.Innate immune restriction and antagonism of viral RNA lacking 2׳-O methylationA molecular arms race between host innate antiviral response and emerging human coronaviruses.Molecular mechanisms of coronavirus RNA capping and methylation.Mutagenesis of S-Adenosyl-l-Methionine-Binding Residues in Coronavirus nsp14 N7-Methyltransferase Demonstrates Differing Requirements for Genome Translation and Resistance to Innate Immunity.Binding of the Methyl Donor S-Adenosyl-l-Methionine to Middle East Respiratory Syndrome Coronavirus 2'-O-Methyltransferase nsp16 Promotes Recruitment of the Allosteric Activator nsp10.Structure-function analysis of severe acute respiratory syndrome coronavirus RNA cap guanine-N7-methyltransferase.Identification and Characterization of a Ribose 2'-O-Methyltransferase Encoded by the Ronivirus Branch of Nidovirales.A compendium of small molecule direct-acting and host-targeting inhibitors as therapies against alphaviruses.Synthesis of 5' cap-0 and cap-1 RNAs using solid-phase chemistry coupled with enzymatic methylation by human (guanine-N⁷)-methyl transferase.Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.DDX5 RNA Helicases: Emerging Roles in Viral Infection.Stratégies de formation de la structure coiffe chez les virus à ARN
P2860
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P2860
Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Crystal Structure and Function ...... ransferase nsp10/nsp16 Complex
@ast
Crystal Structure and Function ...... ransferase nsp10/nsp16 Complex
@en
Crystal Structure and Function ...... ransferase nsp10/nsp16 Complex
@nl
type
label
Crystal Structure and Function ...... ransferase nsp10/nsp16 Complex
@ast
Crystal Structure and Function ...... ransferase nsp10/nsp16 Complex
@en
Crystal Structure and Function ...... ransferase nsp10/nsp16 Complex
@nl
altLabel
Crystal structure and function ...... ransferase nsp10/nsp16 complex
@en
prefLabel
Crystal Structure and Function ...... ransferase nsp10/nsp16 Complex
@ast
Crystal Structure and Function ...... ransferase nsp10/nsp16 Complex
@en
Crystal Structure and Function ...... ransferase nsp10/nsp16 Complex
@nl
P2093
P2860
P50
P921
P1433
P1476
Crystal Structure and Function ...... ransferase nsp10/nsp16 Complex
@en
P2093
Andrew Sharff
Claire Debarnot
Laure Gluais
Mickael Bouvet
Miguel Ortiz-Lombardia
Nicolas Papageorgiou
P2860
P304
P356
10.1371/JOURNAL.PPAT.1002059
P407
P50
P577
2011-05-01T00:00:00Z