A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers
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Cross-Reactivity of TCR Repertoire: Current Concepts, Challenges, and Implication for AllotransplantationImmunological cells and functions in Gaucher diseaseStructural basis of metal hypersensitivityEpitope flexibility and dynamic footprint revealed by molecular dynamics of a pMHC-TCR complexT-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergyPeptide length determines the outcome of TCR/peptide-MHCI engagementA Role for Differential Variable Gene Pairing in Creating T Cell Receptors Specific for Unique Major Histocompatibility LigandsCrossreactivity of a human autoimmune TCR is dominated by a single TCR loopT cell receptor reversed polarity recognition of a self-antigen major histocompatibility complexLack of heterologous cross-reactivity towards HLA-A*02:01 restricted viral epitopes is underpinned by distinct αβT cell receptor signaturesαβ T cell receptors that do not undergo major histocompatibility complex-specific thymic selection possess antibody-like recognition specificitiesMHC restriction is imposed on a diverse T cell receptor repertoire by CD4 and CD8 co-receptors during thymic selectionT cells and their eons-old obsession with MHCMemory NK cells: why do they reside in the liver?Specific increase in potency via structure-based design of a TCR.Diversity-oriented approaches for interrogating T-cell receptor repertoire, ligand recognition, and functionEvolutionarily conserved features contribute to αβ T cell receptor specificityIdentification of a naturally processed HLA-Cw7-binding peptide that cross-reacts with HLA-A24-restricted ovarian cancer-specific CTLs.Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction.Cumulative autoimmunity: T cell clones recognizing several self-epitopes exhibit enhanced pathogenicityStructural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.The T-cell receptor is not hardwired to engage MHC ligands.Recognition of self and altered self by T cells in autoimmunity and allergy.TCRβ repertoire of CD4+ and CD8+ T cells is distinct in richness, distribution, and CDR3 amino acid composition.Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes.Advances in direct T-cell alloreactivity: function, avidity, biophysics and structure.How the TCR balances sensitivity and specificity for the recognition of self and pathogens.Structural and dynamic control of T-cell receptor specificity, cross-reactivity, and binding mechanism.A structural voyage toward an understanding of the MHC-I-restricted immune response: lessons learned and much to be learned.Understanding the complexity and malleability of T-cell recognition.Clinical Role of Human Leukocyte Antigen in Health and Disease.Conserved Vδ1 binding geometry in a setting of locus-disparate pHLA recognition by δ/αβTCRs: insight into recognition of HIV peptides by TCR.SHP-1 Acts as a Key Regulator of Alloresponses by Modulating LFA-1-Mediated Adhesion in Primary Murine T Cells.A study of CDR3 loop dynamics reveals distinct mechanisms of peptide recognition by T-cell receptors exhibiting different levels of cross-reactivity.Sex bias in MHC I-associated shaping of the adaptive immune system.Analysis of CD57+ natural killer cells and CD8+ T lymphocytes in periapical granulomas and radicular cysts.Mycobacterium tuberculosis peptide E7/HLA-DRB1 tetramers with different HLA-DR alleles bound CD4+ T cells might share identical CDR3 region.
P2860
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P2860
A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A Single T Cell Receptor Bound ...... eals Switchable TCR Conformers
@ast
A Single T Cell Receptor Bound ...... eals Switchable TCR Conformers
@en
A Single T Cell Receptor Bound ...... eals Switchable TCR Conformers
@nl
type
label
A Single T Cell Receptor Bound ...... eals Switchable TCR Conformers
@ast
A Single T Cell Receptor Bound ...... eals Switchable TCR Conformers
@en
A Single T Cell Receptor Bound ...... eals Switchable TCR Conformers
@nl
prefLabel
A Single T Cell Receptor Bound ...... eals Switchable TCR Conformers
@ast
A Single T Cell Receptor Bound ...... eals Switchable TCR Conformers
@en
A Single T Cell Receptor Bound ...... eals Switchable TCR Conformers
@nl
P2093
P2860
P50
P3181
P1433
P1476
A Single T Cell Receptor Bound ...... eals Switchable TCR Conformers
@en
P2093
Clamencia Pinilla
Eric Huseby
Frances Crawford
Shaodong Dai
P2860
P3181
P356
10.1016/J.IMMUNI.2011.04.017
P407
P577
2011-07-22T00:00:00Z