Specific increase in potency via structure-based design of a TCR. - Test2 - elhamkhani - TriplyDB

Specific increase in potency via structure-based design of a TCR.

Specific increase in potency via structure-based design of a TCR.

http://www.wikidata.org/entity/Q34383054

about

Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens Structural Model of the Extracellular Assembly of the TCR-CD3 Complex.T-cell receptor gene therapy--ready to go viral?Using Global Analysis to Extend the Accuracy and Precision of Binding Measurements with T cell Receptors and Their Peptide/MHC Ligands.An old Twist in HLA-A: CDR3α Hook up at an R65-joint.A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces.Critical biological parameters modulate affinity as a determinant of function in T-cell receptor gene-modified T-cells.Interpreting T-Cell Cross-reactivity through Structure: Implications for TCR-Based Cancer Immunotherapy.STCRDab: the structural T-cell receptor database.ATLAS: A database linking binding affinities with structures for wild-type and mutant TCR-pMHC complexes.Antitumor activity of CAR-T cells targeting the intracellular oncoprotein WT1 can be enhanced by vaccination

P2860

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P2860

Specific increase in potency via structure-based design of a TCR.

http://www.wikidata.org/entity/Q34383054

description

2014 nî lūn-bûn

@nan

2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Specific increase in potency via structure-based design of a TCR.

@ast

Specific increase in potency via structure-based design of a TCR.

@en

Specific increase in potency via structure-based design of a TCR.

@nl

type

label

Specific increase in potency via structure-based design of a TCR.

@ast

Specific increase in potency via structure-based design of a TCR.

@en

Specific increase in potency via structure-based design of a TCR.

@nl

prefLabel

Specific increase in potency via structure-based design of a TCR.

@ast

Specific increase in potency via structure-based design of a TCR.

@en

Specific increase in potency via structure-based design of a TCR.

@nl

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JIMMUNOL.1302344

P1433

Journal of Immunology

P1476

Specific increase in potency via structure-based design of a TCR.

@en

P2093

Arsen Grigoryan

http://www.w3.org/2001/XMLSchema#string

Karolina Malecek

http://www.w3.org/2001/XMLSchema#string

Laura A Johnson

http://www.w3.org/2001/XMLSchema#string

Michelle Krogsgaard

http://www.w3.org/2001/XMLSchema#string

Shi Zhong

http://www.w3.org/2001/XMLSchema#string

Steven A Rosenberg

http://www.w3.org/2001/XMLSchema#string

Timothy Cardozo

http://www.w3.org/2001/XMLSchema#string

Wei Jun Gu

http://www.w3.org/2001/XMLSchema#string

P2860

Adoptive immunotherapy for cancer: building on success

Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

Cancer regression in patients after transfer of genetically engineered lymphocytes

Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation

Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor

Structures of MART-126/27–35 Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition

A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers

TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms

Increased peptide contacts govern high affinity binding of a modified TCR whilst maintaining a native pMHC docking mode

P304

2587-2599

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P31

scholarly article

P356

10.4049/JIMMUNOL.1302344

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P407

P433

5

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P478

193

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P577

2014-07-28T00:00:00Z

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25070852

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P932

4205480

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