A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca2+/Calmodulin- Dependent Kinase II Holoenzyme - Test2 - elhamkhani - TriplyDB

A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca2+/Calmodulin- Dependent Kinase II Holoenzyme

A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca2+/Calmodulin- Dependent Kinase II Holoenzyme

http://www.wikidata.org/entity/Q27672798

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Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection Postsynaptic signaling during plasticity of dendritic spines L-type calcium channel targeting and local signalling in cardiac myocytes Mechanisms of CaMKII action in long-term potentiation Calmodulin-dependent protein kinase II: linking heart failure and arrhythmias Mechanisms of altered Ca²⁺ handling in heart failure New therapeutic targets in cardiology: arrhythmias and Ca2+/calmodulin-dependent kinase II (CaMKII)An ATP-Competitive Inhibitor Modulates the Allosteric Function of the HER3 Pseudokinase Structural basis for the inhibition of Polo-like kinase 1 Calmodulin regulation of TMEM16A and 16B Ca(2+)-activated chloride channels CaMKII binding to GluN2B is critical during memory consolidation PLGA-Curcumin Attenuates Opioid-Induced Hyperalgesia and Inhibits Spinal CaMKIIα Fast Decay of CaMKII FRET Sensor Signal in Spines after LTP Induction Is Not Due to Its Dephosphorylation.Calcium-calmodulin-dependent protein kinase II isoforms differentially impact the dynamics and structure of the actin cytoskeleton The CaMKII holoenzyme structure in activation-competent conformations High-throughput SAXS for the characterization of biomolecules in solution: a practical approach Nitric oxide induces Ca2+-independent activity of the Ca2+/calmodulin-dependent protein kinase II (CaMKII).Three ways to die suddenly: do they all require calcium calmodulin-dependent protein kinase II?A significant but rather mild contribution of T286 autophosphorylation to Ca2+/CaM-stimulated CaMKII activity.CaMKII activation and dynamics are independent of the holoenzyme structure: an infinite subunit holoenzyme approximation Fluorescence polarization and fluctuation analysis monitors subunit proximity, stoichiometry, and protein complex hydrodynamics Bio-inspired voltage-dependent calcium channel blockers CaMKII binding to GluN2B is differentially affected by macromolecular crowding reagents.Development of a molecularly evolved, highly sensitive CaMKII FRET sensor with improved expression pattern.Covert Changes in CaMKII Holoenzyme Structure Identified for Activation and Subsequent Interactions.Calcium specificity signaling mechanisms in abscisic acid signal transduction in Arabidopsis guard cells Methionine Mistranslation Bypasses the Restraint of the Genetic Code to Generate Mutant Proteins with Distinct Activities.Live imaging of endogenous Ca²⁺/calmodulin-dependent protein kinase II in neurons reveals that ischemia-related aggregation does not require kinase activity CaMKII regulation in information processing and storage.Regulation of DLK-1 kinase activity by calcium-mediated dissociation from an inhibitory isoform Phosphorylation at Ser²⁶ in the ATP-binding site of Ca²⁺/calmodulin-dependent kinase II as a mechanism for switching off the kinase activity.Molecular mechanism of activation-triggered subunit exchange in Ca(2+)/calmodulin-dependent protein kinase II Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition The delicate bistability of CaMKII Phosphoproteomic Analysis Reveals a Novel Mechanism of CaMKIIα Regulation Inversely Induced by Cocaine Memory Extinction versus Reconsolidation Multiple CaMKII Binding Modes to the Actin Cytoskeleton Revealed by Single-Molecule Imaging.Identifying protein kinase target preferences using mass spectrometry.Structural studies on the regulation of Ca2+/calmodulin dependent protein kinase II Apo states of calmodulin and CaBP1 control CaV1 voltage-gated calcium channel function through direct competition for the IQ domain.

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A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca2+/Calmodulin- Dependent Kinase II Holoenzyme

http://www.wikidata.org/entity/Q27672798

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2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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A Mechanism for Tunable Autoin ...... Dependent Kinase II Holoenzyme

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A Mechanism for Tunable Autoin ...... Dependent Kinase II Holoenzyme

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A Mechanism for Tunable Autoin ...... Dependent Kinase II Holoenzyme

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A Mechanism for Tunable Autoin ...... Dependent Kinase II Holoenzyme

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A Mechanism for Tunable Autoin ...... Dependent Kinase II Holoenzyme

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A Mechanism for Tunable Autoin ...... Dependent Kinase II Holoenzyme

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A Mechanism for Tunable Autoin ...... Dependent Kinase II Holoenzyme

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A Mechanism for Tunable Autoin ...... Dependent Kinase II Holoenzyme

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A Mechanism for Tunable Autoin ...... Dependent Kinase II Holoenzyme

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Il-Hyung Lee

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Oren S Rosenberg

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Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation

Determination of domain structure of proteins from X-ray solution scattering

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Crystal structure of a tetradecameric assembly of the association domain of Ca2+/calmodulin-dependent kinase II

PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation

Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation

Coot: model-building tools for molecular graphics

Phasercrystallographic software

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