Atg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy Pathway - Test2 - elhamkhani - TriplyDB

Atg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy Pathway

Atg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy Pathway

http://www.wikidata.org/entity/Q27675398

about

Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress Autophagic processes in yeast: mechanism, machinery and regulation Autophagy modulation as a potential therapeutic target for diverse diseases Atomistic autophagy: the structures of cellular self-digestion Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures Structural basis of ATG3 recognition by the autophagic ubiquitin-like protein ATG12 Structure of the autophagic E2 enzyme Atg10 Expression, purification, and crystal structure of N-terminal domains of human ubiquitin-activating enzyme (E1)Insights into autophagosome maturation revealed by the structures of ATG5 with its interacting partners Size, stoichiometry, and organization of soluble LC3-associated complexes Novel insights into the interaction of UBA5 with UFM1 via a UFM1-interacting sequence.Characterization, crystallization and preliminary X-ray crystallographic analysis of the Uba5 fragment necessary for high-efficiency activation of Ufm1.Autophagic-lysosomal inhibition compromises ubiquitin-proteasome system performance in a p62 dependent manner in cardiomyocytes A semisynthetic Atg3 reveals that acetylation promotes Atg3 membrane binding and Atg8 lipidation.Structural and functional insights to ubiquitin-like protein conjugation.Characterization, crystallization and preliminary X-ray crystallographic analysis of the human Uba5 C-terminus-Ufc1 complex.The Thermotolerant Yeast Kluyveromyces marxianus Is a Useful Organism for Structural and Biochemical Studies of Autophagy.Macromolecular juggling by ubiquitylation enzymes.Plasmodium falciparum erythrocytic stage parasites require the putative autophagy protein PfAtg7 for normal growth.Identification and characterization of the linear region of ATG3 that interacts with ATG7 in higher eukaryotes.Transcriptomic analysis of the autophagy machinery in crustaceans β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy.Characterization of an Autophagy-Related Gene MdATG8i from Apple.Role of Autophagy as a Survival Mechanism for Hypoxic Cells in Tumors.Accurate SAXS profile computation and its assessment by contrast variation experiments Intestinal epithelium and autophagy: partners in gut homeostasis.Autophagy and human diseases.A Complex between Atg7 and Caspase-9: A NOVEL MECHANISM OF CROSS-REGULATION BETWEEN AUTOPHAGY AND APOPTOSIS.Novel pharmacological modulators of autophagy and therapeutic prospects.Two ubiquitin-like conjugation systems that mediate membrane formation during autophagy.The machinery of macroautophagy.Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins.WIPI2b and Atg16L1: setting the stage for autophagosome formation.Co-expression of autophagic markers following photodynamic therapy in SW620 human colon adenocarcinoma cells.Mechanistic study of Uba5 enzyme and the Ufm1 conjugation pathway.Ubiquitin-like Protein Conjugation: Structures, Chemistry, and Mechanism.Structural biology of the macroautophagy machinery Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity.In vitro systems for Atg8 lipidation Enhanced autophagy ameliorates cardiac proteinopathy.

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Atg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy Pathway

http://www.wikidata.org/entity/Q27675398

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2011 nî lūn-bûn

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2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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Atg8 Transfer from Atg7 to Atg ...... anism in the Autophagy Pathway

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Atg8 Transfer from Atg7 to Atg ...... anism in the Autophagy Pathway

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Atg8 Transfer from Atg7 to Atg ...... anism in the Autophagy Pathway

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Atg8 Transfer from Atg7 to Atg ...... anism in the Autophagy Pathway

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Atg8 Transfer from Atg7 to Atg ...... anism in the Autophagy Pathway

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Atg8 Transfer from Atg7 to Atg ...... anism in the Autophagy Pathway

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Active site remodelling accompanies thioester bond formation in the SUMO E1

E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification

Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1

The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation

Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways

Structure of the Escherichia coli ThiS-ThiF complex, a key component of the sulfur transfer system in thiamin biosynthesis

The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: beyond the usual suspects' review series

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Autophagy: molecular machinery for self-eating

Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex

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