E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
about
Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substratesA comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome systemTRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexesControl of cell growth by the SCF and APC/C ubiquitin ligasesThe structure and regulation of Cullin 2 based E3 ubiquitin ligases and their biological functionsE2 enzymes: more than just middle menThe Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and RepairBuilding and remodelling Cullin-RING E3 ubiquitin ligasesA Dual E3 Mechanism for Rub1 Ligation to Cdc53Crystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo PathwaysStructure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding SurfaceA RING E3–substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligasesN-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein ComplexStructural Conservation of Distinctive N-terminal Acetylation-Dependent Interactions across a Family of Mammalian NEDD8 Ligation EnzymesAtg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy PathwayStructure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester TransferE2-binding surface on Uba3 β-grasp domain undergoes a conformational transitionCycle inhibiting factors (cifs): cyclomodulins that usurp the ubiquitin-dependent degradation pathway of host cells.Ubiquitylation, neddylation and the DNA damage responseE2s: structurally economical and functionally repletePerilous journey: a tour of the ubiquitin-proteasome systemInhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3GRbx2 regulates neuronal migration through different cullin 5-RING ligase adaptorsSAG/RBX2 E3 ligase complexes with UBCH10 and UBE2S E2s to ubiquitylate β-TrCP1 via K11-linkage for degradationOvercoming platinum resistance in preclinical models of ovarian cancer using the neddylation inhibitor MLN4924Regulation of parkin and PINK1 by neddylation.Cullin 5 destabilizes Cas to inhibit Src-dependent cell transformation.Pathogenic bacteria target NEDD8-conjugated cullins to hijack host-cell signaling pathwaysAnalysis of the brain palmitoyl-proteome using both acyl-biotin exchange and acyl-resin-assisted capture methods.Reconstruction of an active SOCS3-based E3 ubiquitin ligase complex in vitro: identification of the active components and JAK2 and gp130 as substrates.Comprehensively surveying structure and function of RING domains from Drosophila melanogasterIn vivo RNAi screen reveals neddylation genes as novel regulators of Hedgehog signalingProtein neddylation: beyond cullin-RING ligases.The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy.Twists and turns in ubiquitin-like protein conjugation cascades.Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection.Small RING Finger Proteins RBX1 and RBX2 of SCF E3 Ubiquitin Ligases: The Role in Cancer and as Cancer TargetsNeddylation promotes ubiquitylation and release of Ku from DNA-damage sites.
P2860
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P248
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P2860
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
@ast
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
@en
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
@en-gb
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
@nl
type
label
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
@ast
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
@en
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
@en-gb
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
@nl
altLabel
E2-RING Expansion of the NEDD8 Cascade Confers Specificity to Cullin Modification
@en
prefLabel
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
@ast
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
@en
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
@en-gb
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
@nl
P2093
P2860
P921
P3181
P1433
P1476
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
@en
P2093
Asad M Taherbhoy
Brenda A Schulman
Daniel C Scott
David M Duda
Geoffrey Neale
Harold W Hunt
Laura A Borg
Olivier Ayrault
Peter J Murray
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2009.01.011
P407
P577
2009-02-01T00:00:00Z