CENP-T provides a structural platform for outer kinetochore assembly - Test2 - elhamkhani - TriplyDB

CENP-T provides a structural platform for outer kinetochore assembly

CENP-T provides a structural platform for outer kinetochore assembly

http://www.wikidata.org/entity/Q27675942

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The pseudo GTPase CENP-M drives human kinetochore assembly Protein crystallization screens developed at the MRC Laboratory of Molecular Biology The kinetochore interaction network (KIN) of ascomycetes KNL1: bringing order to the kinetochore Review series: The functions and consequences of force at kinetochores Kinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components.The CENP-T/-W complex is a binding partner of the histone chaperone FACT.Kinetochore biorientation in Saccharomyces cerevisiae requires a tightly folded conformation of the Ndc80 complex.The distinct functions of CENP-C and CENP-T/W in centromere propagation and function in Xenopus egg extracts.Trypanosome outer kinetochore proteins suggest conservation of chromosome segregation machinery across eukaryotes.A new piece in the kinetochore jigsaw puzzle SPC24 is critical for anaplastic thyroid cancer progression.The kinetochore Physicochemical mechanisms of protein regulation by phosphorylation.A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A.The centromere: chromatin foundation for the kinetochore machinery.The architecture of CCAN proteins creates a structural integrity to resist spindle forces and achieve proper Intrakinetochore stretch.The centromere: epigenetic control of chromosome segregation during mitosis The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast.Distinct organization and regulation of the outer kinetochore KMN network downstream of CENP-C and CENP-T The Mps1 kinase modulates the recruitment and activity of Cnn1(CENP-T) at Saccharomyces cerevisiae kinetochores CENP-C is a blueprint for constitutive centromere-associated network assembly within human kinetochores Centromere Protein (CENP)-W Interacts with Heterogeneous Nuclear Ribonucleoprotein (hnRNP) U and May Contribute to Kinetochore-Microtubule Attachment in Mitotic Cells.A quantitative description of Ndc80 complex linkage to human kinetochores Inner Kinetochore Protein Interactions with Regional Centromeres of Fission Yeast.Regulation of outer kinetochore Ndc80 complex-based microtubule attachments by the central kinetochore Mis12/MIND complex.Dynamic changes in CCAN organization through CENP-C during cell-cycle progression.Stepwise unfolding supports a subunit model for vertebrate kinetochores Whole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore.The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly A novel prognostic biomarker SPC24 up-regulated in hepatocellular carcinoma.CDK-dependent phosphorylation and nuclear exclusion coordinately control kinetochore assembly state.Evolutionary Turnover of Kinetochore Proteins: A Ship of Theseus?Coupling unbiased mutagenesis to high-throughput DNA sequencing uncovers functional domains in the Ndc80 kinetochore protein of Saccharomyces cerevisiae.The centromeric nucleosome-like CENP-T-W-S-X complex induces positive supercoils into DNA.Molecular basis of outer kinetochore assembly on CENP-T.A CENP-S/X complex assembles at the centromere in S and G2 phases of the human cell cycle.Anarchic centromeres: deciphering order from apparent chaos.Linked in: formation and regulation of microtubule attachments during chromosome segregation.

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CENP-T provides a structural platform for outer kinetochore assembly

http://www.wikidata.org/entity/Q27675942

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2013 nî lūn-bûn

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2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի փետրվարին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

CENP-T provides a structural platform for outer kinetochore assembly

@ast

CENP-T provides a structural platform for outer kinetochore assembly

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CENP-T provides a structural platform for outer kinetochore assembly

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label

CENP-T provides a structural platform for outer kinetochore assembly

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CENP-T provides a structural platform for outer kinetochore assembly

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CENP-T provides a structural platform for outer kinetochore assembly

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prefLabel

CENP-T provides a structural platform for outer kinetochore assembly

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CENP-T provides a structural platform for outer kinetochore assembly

@en

CENP-T provides a structural platform for outer kinetochore assembly

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P1433

The EMBO Journal

P1476

CENP-T provides a structural platform for outer kinetochore assembly

@en

P2093

Florencia Rago

http://www.w3.org/2001/XMLSchema#string

Tatsuo Fukagawa

http://www.w3.org/2001/XMLSchema#string

Tetsuya Hori

http://www.w3.org/2001/XMLSchema#string

P2860

Intrinsically unstructured proteins and their functions

Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1

Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes

A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension

CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold

The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment

A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1

The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.

The conserved KMN network constitutes the core microtubule-binding site of the kinetochore

CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore

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424-436

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scholarly article

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2763189

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10.1038/EMBOJ.2012.348

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P433

3

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32

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Iain M Cheeseman

Tatsuya Nishino

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2013-01-18T00:00:00Z

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234166903

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23334297

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3567495

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