The architecture of CCAN proteins creates a structural integrity to resist spindle forces and achieve proper Intrakinetochore stretch. - Test2 - elhamkhani - TriplyDB

The architecture of CCAN proteins creates a structural integrity to resist spindle forces and achieve proper Intrakinetochore stretch.

The architecture of CCAN proteins creates a structural integrity to resist spindle forces and achieve proper Intrakinetochore stretch.

http://www.wikidata.org/entity/Q34541397

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Stable kinetochore-microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells Decoding Polo-like kinase 1 signaling along the kinetochore-centromere axis Connecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.Heterogeneous architecture of vertebrate kinetochores revealed by three-dimensional superresolution fluorescence microscopy.The distinct functions of CENP-C and CENP-T/W in centromere propagation and function in Xenopus egg extracts.The Inner Centromere Protein (INCENP) Coil Is a Single α-Helix (SAH) Domain That Binds Directly to Microtubules and Is Important for Chromosome Passenger Complex (CPC) Localization and Function in Mitosis.The Mps1 kinase modulates the recruitment and activity of Cnn1(CENP-T) at Saccharomyces cerevisiae kinetochores CENP-C is a blueprint for constitutive centromere-associated network assembly within human kinetochores A quantitative description of Ndc80 complex linkage to human kinetochores Stepwise unfolding supports a subunit model for vertebrate kinetochores Whole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore.The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface Bistability of a coupled Aurora B kinase-phosphatase system in cell division.How the kinetochore couples microtubule force and centromere stretch to move chromosomes Genomic variation within alpha satellite DNA influences centromere location on human chromosomes with metastable epialleles.Mechanisms to Avoid and Correct Erroneous Kinetochore-Microtubule Attachments.A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis.A Molecular View of Kinetochore Assembly and Function.Tension sensors reveal how the kinetochore shares its load.Human kinetochores are swivel joints that mediate microtubule attachments.The Ska complex promotes Aurora B activity to ensure chromosome biorientation.Aurora A Kinase Contributes to a Pole-Based Error Correction Pathway.Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2-Mediated Phosphorylation of CENP-A.A defect in the inner kinetochore protein CENPT causes a new syndrome of severe growth failure.The Ins and Outs of Aurora B Inner Centromere Localization.Nucleolar and spindle-associated protein 1 (NUSAP1) interacts with a SUMO E3 ligase complex during chromosome segregation.Critical Foundation of the Kinetochore: The Constitutive Centromere-Associated Network (CCAN).An optimized method for 3D fluorescence co-localization applied to human kinetochore protein architecture.Simultaneous Manipulation and Super-Resolution Fluorescence Imaging of Individual Kinetochores Coupled to Microtubule Tips.Measuring Kinetochore-Microtubule Attachment Stability in Cultured Cells.Complete microtubule-kinetochore occupancy favours the segregation of merotelic attachments.Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80

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P2860

The architecture of CCAN proteins creates a structural integrity to resist spindle forces and achieve proper Intrakinetochore stretch.

http://www.wikidata.org/entity/Q34541397

description

2014 nî lūn-bûn

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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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The architecture of CCAN prote ...... oper Intrakinetochore stretch.

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The architecture of CCAN prote ...... oper Intrakinetochore stretch.

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The architecture of CCAN prote ...... oper Intrakinetochore stretch.

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The architecture of CCAN prote ...... oper Intrakinetochore stretch.

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The architecture of CCAN prote ...... oper Intrakinetochore stretch.

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The architecture of CCAN prote ...... oper Intrakinetochore stretch.

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The architecture of CCAN prote ...... oper Intrakinetochore stretch.

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The architecture of CCAN prote ...... oper Intrakinetochore stretch.

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The architecture of CCAN prote ...... oper Intrakinetochore stretch.

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J.DEVCEL.2014.08.003

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Developmental Cell

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The architecture of CCAN prote ...... oper Intrakinetochore stretch.

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P2093

Aussie Suzuki

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Benjamin L Badger

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Edward D Salmon

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Jennifer G DeLuca

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Xiaohu Wan

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P2860

Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes

CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold

Genome stability is ensured by temporal control of kinetochore-microtubule dynamics

Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites.

KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates

Review series: The functions and consequences of force at kinetochores

Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex.

The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment

A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors

CENP-T provides a structural platform for outer kinetochore assembly

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717-730

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scholarly article

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10.1016/J.DEVCEL.2014.08.003

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6

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30

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25268173

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4237209

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