RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover - Test2 - elhamkhani - TriplyDB

RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover

RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover

http://www.wikidata.org/entity/Q27676229

about

Integrin cytoplasmic tail interactions Talin Dependent Mechanosensitivity of Cell Focal Adhesions The talin head domain reinforces integrin-mediated adhesion by promoting adhesion complex stability and clustering Vinculin controls talin engagement with the actomyosin machinery.All Subdomains of the Talin Rod Are Mechanically Vulnerable and May Contribute To Cellular Mechanosensing A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity.Integrin-associated complexes form hierarchically with variable stoichiometry in nascent adhesions Cooperative Vinculin Binding to Talin Mapped by Time-Resolved Super Resolution Microscopy.Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis.Mechanical stability of talin rod controls cell migration and substrate sensing.Vinculin in cell-cell and cell-matrix adhesions.Talins and kindlins: partners in integrin-mediated adhesion.A four actin-binding protein signature model for poor prognosis of patients with esophageal squamous cell carcinoma Structural and mechanistic insights into the recruitment of talin by RIAM in integrin signaling Talin determines the nanoscale architecture of focal adhesions.Loss of the Rap1 effector RIAM results in leukocyte adhesion deficiency due to impaired β2 integrin function in mice Leukocyte arrest: Biomechanics and molecular mechanisms of β2 integrin activation LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex The mechanical response of talin.Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions.Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation.Calpain-dependent cytoskeletal rearrangement exploited for anthrax toxin endocytosis.Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation.Mechanisms of talin-dependent integrin signaling and crosstalk Protein conformation as a regulator of cell-matrix adhesion.Integrin function in vascular biology: a view from 2013.The importance of podocyte adhesion for a healthy glomerulus.Alternative mechanisms for talin to mediate integrin function Molecular stretching modulates mechanosensing pathways.Talin - the master of integrin adhesions.In vivo quantitative analysis of Talin turnover in response to force.Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion.Talin autoinhibition is required for morphogenesis.Structure calculation, refinement and validation using CcpNmr Analysis.Mechanisms of integrin and filamin binding and their interplay with talin during early focal adhesion formation.Molecular Simulations Suggest a Force-Dependent Mechanism of Vinculin Activation.Phosphatidylinositol 4,5-Bisphosphate Modulates the Affinity of Talin-1 for Phospholipid Bilayers and Activates Its Autoinhibited Form.Vinculin regulates assembly of talin: β3 integrin complexes.Vinculin Force-Sensitive Dynamics at Focal Adhesions Enable Effective Directed Cell Migration.

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P2860

RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover

http://www.wikidata.org/entity/Q27676229

description

2013 nî lūn-bûn

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2013 թուականի Մարտին հրատարակուած գիտական յօդուած

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2013 թվականի մարտին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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RIAM and Vinculin Binding to T ...... Adhesion Assembly and Turnover

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RIAM and Vinculin Binding to T ...... Adhesion Assembly and Turnover

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RIAM and Vinculin Binding to T ...... Adhesion Assembly and Turnover

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RIAM and Vinculin Binding to T ...... Adhesion Assembly and Turnover

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RIAM and Vinculin Binding to T ...... Adhesion Assembly and Turnover

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RIAM and Vinculin Binding to T ...... Adhesion Assembly and Turnover

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RIAM and Vinculin Binding to T ...... Adhesion Assembly and Turnover

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RIAM and Vinculin Binding to T ...... Adhesion Assembly and Turnover

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JBC.M112.438119

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Journal of Biological Chemistry

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RIAM and vinculin binding to t ...... adhesion assembly and turnover

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P2093

David R Critchley

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Fiona Hey

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Igor L Barsukov

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Neil Bate

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Paul R Elliott

http://www.w3.org/2001/XMLSchema#string

Ricky Tsang

http://www.w3.org/2001/XMLSchema#string

Thomas Zacharchenko

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P2860

Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics

Identification of a repeated domain within mammalian alpha-synemin that interacts directly with talin

Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

Ena/VASP: towards resolving a pointed controversy at the barbed end

Vinculin activation by talin through helical bundle conversion

The structure of the C-terminal actin-binding domain of talin

Structural Determinants of Integrin Binding to the Talin Rod

The Structure of an Interdomain Complex That Regulates Talin Activity

The structure of an integrin/talin complex reveals the basis of inside-out signal transduction.

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8238-8249

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scholarly article

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1192490

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10.1074/JBC.M112.438119

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12

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288

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Alexandre R Gingras

Christoph Ballestrem

Benjamin T Goult

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2013-02-06T00:00:00Z

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235415532

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23389036

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3605642

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