Structural and Biochemical Characterization of Human Mitochondrial Branched-chain -Ketoacid Dehydrogenase Phosphatase
about
Benzothiophene carboxylate derivatives as novel allosteric inhibitors of branched-chain α-ketoacid dehydrogenase kinaseStructure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase.Two novel mutations in the BCKDK (branched-chain keto-acid dehydrogenase kinase) gene are responsible for a neurobehavioral deficit in two pediatric unrelated patientsIntegration and global analysis of isothermal titration calorimetry data for studying macromolecular interactions.SEDPHAT--a platform for global ITC analysis and global multi-method analysis of molecular interactions.Binding of a third metal ion by the human phosphatases PP2Cα and Wip1 is required for phosphatase activityGenetic determinant for amino acid metabolites and changes in body weight and insulin resistance in response to weight-loss diets: the Preventing Overweight Using Novel Dietary Strategies (POUNDS LOST) trial.Enzymes involved in branched-chain amino acid metabolism in humans.A novel regulatory defect in the branched-chain α-keto acid dehydrogenase complex due to a mutation in the PPM1K gene causes a mild variant phenotype of maple syrup urine disease.Conformational Changes in Active and Inactive States of Human PP2Cα Characterized by Hydrogen/Deuterium Exchange-Mass Spectrometry.PPM1K dephosphorylates p-BCKDHGenetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels.
P2860
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P2860
Structural and Biochemical Characterization of Human Mitochondrial Branched-chain -Ketoacid Dehydrogenase Phosphatase
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Structural and Biochemical Cha ...... acid Dehydrogenase Phosphatase
@ast
Structural and Biochemical Cha ...... acid Dehydrogenase Phosphatase
@en
Structural and Biochemical Cha ...... acid Dehydrogenase Phosphatase
@nl
type
label
Structural and Biochemical Cha ...... acid Dehydrogenase Phosphatase
@ast
Structural and Biochemical Cha ...... acid Dehydrogenase Phosphatase
@en
Structural and Biochemical Cha ...... acid Dehydrogenase Phosphatase
@nl
prefLabel
Structural and Biochemical Cha ...... acid Dehydrogenase Phosphatase
@ast
Structural and Biochemical Cha ...... acid Dehydrogenase Phosphatase
@en
Structural and Biochemical Cha ...... acid Dehydrogenase Phosphatase
@nl
P2093
P2860
P356
P1476
Structural and Biochemical Cha ...... acid Dehydrogenase Phosphatase
@en
P2093
David T Chuang
Jacinta L Chuang
R Max Wynn
P2860
P304
P356
10.1074/JBC.M111.314963
P407
P577
2012-03-16T00:00:00Z