Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system
about
Nucleoside modifications in the regulation of gene expression: focus on tRNAFrom Prebiotics to Probiotics: The Evolution and Functions of tRNA ModificationsThe universal tree of life: an updateDiversity of the biosynthesis pathway for threonylcarbamoyladenosine (t(6)A), a universal modification of tRNAStructure ofSaccharomyces cerevisiaemitochondrial Qri7 in complex with AMPStructural and functional characterization of KEOPS dimerization by Pcc1 and its role in t6A biosynthesisFunctional assignment of KEOPS/EKC complex subunits in the biosynthesis of the universal t6A tRNA modification.Kinase-associated endopeptidase 1 (Kae1) participates in an atypical ribosome-associated complex in the apicoplast of Plasmodium falciparumDiscovery of the β-barrel-type RNA methyltransferase responsible for N6-methylation of N6-threonylcarbamoyladenosine in tRNAsProteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7NMR-based Structural Analysis of Threonylcarbamoyl-AMP Synthase and Its Substrate Interactions.A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs.Cross kingdom functional conservation of the core universally conserved threonylcarbamoyladenosine tRNA synthesis enzymesPredicting the minimal translation apparatus: lessons from the reductive evolution of mollicutes.An extensive allelic series of Drosophila kae1 mutants reveals diverse and tissue-specific requirements for t6A biogenesis.Essentiality of threonylcarbamoyladenosine (t(6)A), a universal tRNA modification, in bacteria.Nuclear-encoded factors involved in post-transcriptional processing and modification of mitochondrial tRNAs in human disease.Genome-wide studies of telomere biology in budding yeastA global genetic interaction network maps a wiring diagram of cellular function.tRNA N6-adenosine threonylcarbamoyltransferase defect due to KAE1/TCS3 (OSGEP) mutation manifest by neurodegeneration and renal tubulopathy.Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli.Global translational impacts of the loss of the tRNA modification t6A in yeast.Structure and mechanism of a bacterial t6A biosynthesis system.The mitochondrial epitranscriptome: the roles of RNA modifications in mitochondrial translation and human disease.Structure-function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t6A tRNA modification.A natural non-Watson-Crick base pair in human mitochondrial tRNAThr causes structural and functional susceptibility to local mutations.The structure of the TsaB/TsaD/TsaE complex reveals an unexpected mechanism for the bacterial t6A tRNA-modification.CO2-sensitive tRNA modification associated with human mitochondrial disease.
P2860
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P2860
Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system
description
2013 nî lūn-bûn
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2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Reconstitution and characteriz ...... using a minimal enzyme system
@ast
Reconstitution and characteriz ...... using a minimal enzyme system
@en
Reconstitution and characteriz ...... using a minimal enzyme system
@nl
type
label
Reconstitution and characteriz ...... using a minimal enzyme system
@ast
Reconstitution and characteriz ...... using a minimal enzyme system
@en
Reconstitution and characteriz ...... using a minimal enzyme system
@nl
prefLabel
Reconstitution and characteriz ...... using a minimal enzyme system
@ast
Reconstitution and characteriz ...... using a minimal enzyme system
@en
Reconstitution and characteriz ...... using a minimal enzyme system
@nl
P2093
P2860
P50
P3181
P356
P1476
Reconstitution and characteriz ...... using a minimal enzyme system
@en
P2093
Daniel Y L Mao
Dante Neculai
David Chiovitti
Elena Lissina
Gennadiy Poda
Igor Kurinov
Jonathan Strecker
Leo C K Wan
Neroshan Thevakumaran
P2860
P304
P3181
P356
10.1093/NAR/GKT322
P407
P577
2013-07-01T00:00:00Z