In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide - Test2 - elhamkhani - TriplyDB

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

http://www.wikidata.org/entity/Q27679062

about

Plant antimicrobial peptides as potential anticancer agents Cyclic and Macrocyclic Peptides as Chemical Tools To Recognise Protein Surfaces and Probe Protein-Protein Interactions Advanced Developments in Cyclic Polymers: Synthesis, Applications, and Perspectives Structural Insights into the Role of the Cyclic Backbone in a Squash Trypsin Inhibitor Semienzymatic Cyclization of Disulfide-rich Peptides Using Sortase A Structure of a complex formed by a protein and a helical aromatic oligoamide foldamer at 2.1 Å resolution Protein grafting of p53TAD onto a leucine zipper scaffold generates a potent HDM dual inhibitor Racemic and quasi-racemic X-ray structures of cyclic disulfide-rich peptide drug scaffolds Transforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxins A current perspective on applications of macrocyclic-peptide-based high-affinity ligands Artificial disulfide-rich peptide scaffolds with precisely defined disulfide patterns and a minimized number of isomers.Asteropsins B-D, sponge-derived knottins with potential utility as a novel scaffold for oral peptide drugs Optimization of the cyclotide framework to improve cell penetration properties.The evolution of Momordica cyclic peptides.Rapid parallel synthesis of bioactive folded cyclotides by using a tea-bag approach.Inhibition of Human Prolyl Oligopeptidase Activity by the Cyclotide Psysol 2 Isolated from Psychotria solitudinum.Cystine-knot peptides targeting cancer-relevant human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).Recombinant Expression and Phenotypic Screening of a Bioactive Cyclotide Against α-Synuclein-Induced Cytotoxicity in Baker's Yeast.Review seed biopharmaceutical cyclic peptides: From discovery to applications.Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold.Full Sequence Amino Acid Scanning of θ-Defensin RTD-1 Yields a Potent Anthrax Lethal Factor Protease Inhibitor.Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration.Targeting intracellular protein-protein interactions with cell-permeable cyclic peptides.Design of a MCoTI-Based Cyclotide with Angiotensin (1-7)-Like Activity.Chemical and biological production of cyclotides.Disulfide Bridges: Bringing Together Frustrated Structure in a Bioactive Peptide.Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy.Immunosuppressive peptides and their therapeutic applications.Cystine-knot peptides: emerging tools for cancer imaging and therapy.Cyclotides: a natural combinatorial peptide library or a bioactive sequence player?New Modalities for Challenging Targets in Drug Discovery.Modulating protein-protein interactions: the potential of peptides.Strategies to stabilize cell penetrating peptides for in vivo applications.Cellular uptake of a cystine-knot peptide and modulation of its intracellular trafficking.Approaches to the stabilization of bioactive epitopes by grafting and peptide cyclization.Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamilies.Discovery, structure, function, and applications of cyclotides: circular proteins from plants.Discovery and optimization of peptide macrocycles.The role of disulfide bonds in structure and activity of chlorotoxin.

P2860

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P2860

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

http://www.wikidata.org/entity/Q27679062

description

2013 nî lūn-bûn

@nan

2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

@ast

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

@en

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

@nl

type

label

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

@ast

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

@en

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

@nl

prefLabel

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

@ast

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

@en

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

@nl

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Journal of the American Chemical Society

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In vivo activation of the p53 tumor suppressor pathway by an engineered cyclotide

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Ahmed Y Elnagar

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Julio A Camarero

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Melissa Millard

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Nouri Neamati

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Radhika Borra

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Subhabrata Majumder

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Tao Bi

http://www.w3.org/2001/XMLSchema#string

Yanbin Ji

http://www.w3.org/2001/XMLSchema#string

P2860

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

MDMX: a novel p53-binding protein with some functional properties of MDM2

Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain

Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX

Apamin as a novel template for structure-based rational design of potent peptide activators of p53

Systematic Mutational Analysis of Peptide Inhibition of the p53–MDM2/MDMX Interactions

Elucidation of the primary and three-dimensional structure of the uterotonic polypeptide kalata B1

Regulation of p53 stability by Mdm2

Synthesis of proteins by native chemical ligation

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11623-11633

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scholarly article

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3007572

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10.1021/JA405108P

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31

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135

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Alexander Shekhtman

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2013-07-25T00:00:00Z

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249317536

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23848581

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3767463

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