Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold.
about
Targeting kinase signaling pathways with constrained peptide scaffolds.Oral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis.The chimeric ubiquitin ligase SH2-U-box inhibits the growth of imatinib-sensitive and resistant CML by targeting the native and T315I-mutant BCR-ABLConservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodiesDual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy.New Modalities for Challenging Targets in Drug Discovery.Discovery and optimization of peptide macrocycles.Cyclotides: Overview and Biotechnological Applications.Cyclotides, a versatile ultrastable micro-protein scaffold for biotechnological applications.Discovery of Non-ATP-Competitive Inhibitors of Polo-like Kinase 1.Anthelmintic niclosamide suppresses transcription of BCR-ABL fusion oncogene via disabling Sp1 and induces apoptosis in imatinib-resistant CML cells harboring T315I mutant.Biodistribution of the cyclotide MCoTI-II, a cyclic disulfide-rich peptide drug scaffold.The N-terminal pro-domain of the kalata B1 cyclotide precursor is intrinsically unstructured.
P2860
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P2860
Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold.
@ast
Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold.
@en
type
label
Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold.
@ast
Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold.
@en
prefLabel
Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold.
@ast
Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold.
@en
P2860
P50
P356
P1433
P1476
Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold.
@en
P2093
Louise Thorstholm
P2860
P2888
P356
10.1038/SREP12974
P407
P577
2015-08-12T00:00:00Z