Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
about
Inactivation of the Mycobacterium tuberculosis Antigen 85 Complex by Covalent, Allosteric InhibitorsRepurposing Clinical Molecule Ebselen to Combat Drug Resistant PathogensMycobacterium tuberculosis Thioredoxin Reductase Is Essential for Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant DefenseThe three Mycobacterium tuberculosis antigen 85 isoforms have unique substrates and activities determined by non-active site regions.The mycobacterial cell envelope-lipidsEbselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replicationThe cell envelope glycoconjugates of Mycobacterium tuberculosisCovalent modification of the Mycobacterium tuberculosis FAS-II dehydratase by Isoxyl and Thiacetazone.Repurposing Non-Antimicrobial Drugs and Clinical Molecules to Treat Bacterial InfectionsSynthesis and evaluation of new 2-aminothiophenes against Mycobacterium tuberculosis.Thermal and Photoinduced Copper-Promoted C-Se Bond Formation: Synthesis of 2-Alkyl-1,2-benzisoselenazol-3(2H)-ones and Evaluation against Mycobacterium tuberculosis.Exploring Covalent Allosteric Inhibition of Antigen 85C from Mycobacterium tuberculosis by Ebselen Derivatives.Targeting the trehalose utilization pathways of Mycobacterium tuberculosisEbselen induces reactive oxygen species (ROS)-mediated cytotoxicity in Saccharomyces cerevisiae with inhibition of glutamate dehydrogenase being a target.Secretome Prediction of Two M. tuberculosis Clinical Isolates Reveals Their High Antigenic Density and Potential Drug Targets.Visualization of mycobacterial membrane dynamics in live cells.Ebselen, a promising antioxidant drug: mechanisms of action and targets of biological pathways.Small Molecules That Sabotage Bacterial Virulence.Synergistic antibacterial effect of silver and ebselen against multidrug-resistant Gram-negative bacterial infections.A small-molecule antivirulence agent for treating Clostridium difficile infection.Benefits of Genomic Insights and CRISPR-Cas Signatures to Monitor Potential Pathogens across Drinking Water Production and Distribution Systems.Bioorthogonal Chemical Reporters for Selective In Situ Probing of Mycomembrane Components in Mycobacteria.An Antibacterial β-Lactone Kills Mycobacterium tuberculosis by Disrupting Mycolic Acid Biosynthesis.Acute modulation of mycobacterial cell envelope biogenesis by front-line TB drugs.Cyclipostins and Cyclophostin analogs inhibit the antigen 85C from Mycobacterium tuberculosis both in vitro and in vivo.Mycolyltransferase from Mycobacterium tuberculosis in covalent complex with tetrahydrolipstatin provides insights into Antigen 85 catalysis.Functional insights from a comparative study on the dynamics of Antigen85 proteins and MPT51 from Mycobacterium tuberculosis.Imaging mycobacterial growth and division with a fluorogenic probe.Rapid detection of Mycobacterium tuberculosis in sputum with a solvatochromic trehalose probe.Glucosylglycerate metabolism, bioversatility and mycobacterial survival.
P2860
Q27684704-B821032D-656A-4B5F-A758-6B1EA9CB3562Q28546863-F6C8EF58-23D7-4536-BAD7-395282C95BA1Q28552573-82E85C85-BCD8-4867-8EE9-88544441CC61Q34139044-903E692D-1553-4110-827F-5D5CDEA50187Q34355375-FF769CF3-CC73-4940-B3E4-B15795837C9CQ34361091-1FF5235F-2550-4DCD-B369-DB5BD741D12DQ34423962-4E7C1FBE-5CE4-40FF-9715-B609A9BD37DAQ35461578-78AE42CF-1BEA-4134-8EB3-0080A86F9764Q35626649-58A5E7A0-84F1-4132-B805-5492DAC3D909Q36037140-416169BB-5171-428D-B57D-FB49C97F9FABQ36301023-DA748315-0D6E-441A-9227-1F70A40B1076Q36305447-88154195-B46E-4874-88C9-73D1A2A2A14EQ36629840-6C774F82-B430-4F6C-971E-02332E0DE5CEQ37535003-C63BBD8C-3581-4DC2-AA9F-DB31094E90D1Q37627084-2690F63F-E598-44AC-9BA3-08033B6492C4Q37692416-2B70B068-9E00-4E8D-95F0-72F2E71AD8F5Q38215395-7653B81C-53BE-466C-B58D-564EE7CBAC9AQ39139601-76382EF3-9CA0-4961-98BE-00E2FA2650EBQ40175261-AF4E29F7-9E2A-4DD0-8209-CCA5F0258E65Q40984710-D7E9C5D4-04AC-4733-87B1-C9A73C925101Q46269762-389C34CC-763D-45DE-88CD-BDDD80CB97E7Q46611953-A95588E5-FB16-4E79-8DED-A58AE1E2DD5FQ47606759-1B10CE27-8747-437E-92E5-31E887279558Q48515500-EC2A657F-FB5A-4CEC-AD71-EC227CC75B9DQ48550005-6BAC489B-8CB6-4A47-A580-404EA45B006DQ49911385-529A91F2-4A16-449B-BC08-C023788EA66FQ50855542-E0ED7DC6-4B6E-4A44-B0FA-12A971D5CE1EQ52716127-01EEA6C9-E51B-4793-93C4-425BE70E4525Q53701664-33DB12DE-F263-481C-9464-6AF2B9189B6BQ53756182-9F093321-49A4-479C-AE4A-8DE599F73EA4
P2860
Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
@ast
Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
@en
Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
@nl
type
label
Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
@ast
Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
@en
Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
@nl
prefLabel
Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
@ast
Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
@en
Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
@nl
P2093
P2860
P3181
P356
P1476
Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen
@en
P2093
Anna E Grzegorzewicz
Daniel H Lajiness
Dragan Isailovic
Julie Boucau
Lorenza Favrot
Rachel K Marvin
P2860
P2888
P3181
P356
10.1038/NCOMMS3748
P407
P577
2013-01-01T00:00:00Z
P5875
P6179
1035112927