Genetic and Molecular Basis of Drug Resistance and Species-Specific Drug Action in Schistosome Parasites - Test2 - elhamkhani - TriplyDB

Genetic and Molecular Basis of Drug Resistance and Species-Specific Drug Action in Schistosome Parasites

Genetic and Molecular Basis of Drug Resistance and Species-Specific Drug Action in Schistosome Parasites

http://www.wikidata.org/entity/Q27680669

about

Schistosomiasis as a disease of stem cells Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine Drug-induced exposure of Schistosoma mansoni antigens SmCD59a and SmKK7 The NIH-NIAID Schistosomiasis Resource Center at the Biomedical Research Institute: Molecular Redux Application of RNAi to Genomic Drug Target Validation in Schistosomes The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni Exploring molecular variation in Schistosoma japonicum in China Ivermectin - Old Drug, New Tricks?The contribution of mass drug administration to global health: past, present and future.Independent origins of loss-of-function mutations conferring oxamniquine resistance in a Brazilian schistosome population.Exposure to hycanthone alters chromatin structure around specific gene functions and specific repeats in Schistosoma mansoni Efficient linkage mapping using exome capture and extreme QTL in schistosome parasites.Ion channels and drug transporters as targets for anthelmintics.Structure-function analysis of apical membrane-associated molecules of the tegument of schistosome parasites of humans: prospects for identification of novel targets for parasite control.New insights into the genetic diversity of Schistosoma mansoni and S. haematobiumin Yemen Can human schistosomiasis mansoni control be sustained in high-risk transmission foci in Egypt?Whole genome resequencing of the human parasite Schistosoma mansoni reveals population history and effects of selection Schistosome infectivity in the snail, Biomphalaria glabrata, is partially dependent on the expression of Grctm6, a Guadeloupe Resistance Complex protein Real-time PCR for sexing Schistosoma mansoni cercariae.WormBase ParaSite - a comprehensive resource for helminth genomics.Monitoring the efficacy of drugs for neglected tropical diseases controlled by preventive chemotherapy.Hybridizations within the Genus Schistosoma: implications for evolution, epidemiology and control.Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity.Something old, something new: is praziquantel enough for schistosomiasis control?(Epi)genetic Inheritance in Schistosoma mansoni: A Systems Approach.Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy.Inhibition of Tapeworm Thioredoxin and Glutathione Pathways by an Oxadiazole N-Oxide Leads to Reduced Mesocestoides vogae Infection Burden in Mice.Clearance of schistosome parasites by resistant genotypes at a single genomic region in Biomphalaria glabrata snails involves cellular components of the hemolymph.Polypyridylruthenium(II) complexes exert in vitro and in vivo nematocidal activity and show significant inhibition of parasite acetylcholinesterases.A genome resequencing-based genetic map reveals the recombination landscape of an outbred parasitic nematode in the presence of polyploidy and polyandry.Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite acetylcholinesterases.Antischistosomal agents: state of art and perspectives.How has the genomics era impacted schistosomiasis drug discovery?Pleiotropic alterations in gene expression in Latin American Fasciola hepatica isolates with different susceptibility to drugs.Schistosomiasis therapeutics: whats in the pipeline?Drug Repurposing for Schistosomiasis: Combinations of Drugs or Biomolecules.Strongyloides stercoralis and relatives: recent advances in general and molecular biology.Clonal amplification of Fasciola hepatica in Galba truncatula: within and between isolate variation of triclabendazole-susceptible and -resistant clones.

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Genetic and Molecular Basis of Drug Resistance and Species-Specific Drug Action in Schistosome Parasites

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A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni

Whole-genome sequence of Schistosoma haematobium

The genome of the blood fluke Schistosoma mansoni

The Schistosoma japonicum genome reveals features of host-parasite interplay.

Rescuing the bottom billion through control of neglected tropical diseases

The HHpred interactive server for protein homology detection and structure prediction

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Automated structure solution with autoSHARP

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