Application of RNAi to Genomic Drug Target Validation in Schistosomes
about
Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoniHigh-throughput screening against thioredoxin glutathione reductase identifies novel inhibitors with potential therapeutic value for schistosomiasisMolecular characterization of host-parasite cell signalling in Schistosoma mansoni during early development.Schistosome infectivity in the snail, Biomphalaria glabrata, is partially dependent on the expression of Grctm6, a Guadeloupe Resistance Complex proteinDefining the Schistosoma haematobium kinome enables the prediction of essential kinases as anti-schistosome drug targets.Calmodulin disruption impacts growth and motility in juvenile liver fluke.Clearance of schistosome parasites by resistant genotypes at a single genomic region in Biomphalaria glabrata snails involves cellular components of the hemolymph.
P2860
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P2860
Application of RNAi to Genomic Drug Target Validation in Schistosomes
description
2015 nî lūn-bûn
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2015 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2015 թվականի մայիսին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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name
Application of RNAi to Genomic Drug Target Validation in Schistosomes
@ast
Application of RNAi to Genomic Drug Target Validation in Schistosomes
@en
Application of RNAi to Genomic Drug Target Validation in Schistosomes
@nl
type
label
Application of RNAi to Genomic Drug Target Validation in Schistosomes
@ast
Application of RNAi to Genomic Drug Target Validation in Schistosomes
@en
Application of RNAi to Genomic Drug Target Validation in Schistosomes
@nl
prefLabel
Application of RNAi to Genomic Drug Target Validation in Schistosomes
@ast
Application of RNAi to Genomic Drug Target Validation in Schistosomes
@en
Application of RNAi to Genomic Drug Target Validation in Schistosomes
@nl
P2093
P2860
P3181
P1476
Application of RNAi to Genomic Drug Target Validation in Schistosomes
@en
P2093
Alessandra Guidi
Andrew L Hopkins
Ian M Carruthers
Nuha R Mansour
Quentin D Bickle
Ross A Paveley
P2860
P304
P3181
P356
10.1371/JOURNAL.PNTD.0003801
P407
P577
2015-05-20T00:00:00Z