Nicotine and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Binding and Access Channel in Human Cytochrome P450 2A6 and 2A13 Enzymes
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Challenging Density Functional Theory Calculations with Hemes and PorphyrinsStructural diversity of eukaryotic membrane cytochrome p450sConformational Adaptation of Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4 Revealed upon Binding Multiple Amlodipine MoleculesStructural basis for the 4'-hydroxylation of diclofenac by a microbial cytochrome P450 monooxygenaseMOLE 2.0: advanced approach for analysis of biomacromolecular channelsContributions of ionic interactions and protein dynamics to cytochrome P450 2D6 (CYP2D6) substrate and inhibitor binding.Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity.Binding of diverse environmental chemicals with human cytochromes P450 2A13, 2A6, and 1B1 and enzyme inhibition.The role of cytochrome P450 2B6 and 2B4 substrate access channel residues predicted based on crystal structures of the amlodipine complexesA numerical method for analysis of in vitro time-dependent inhibition data. Part 2. Application to experimental data.Three-dimensional quantitative structure-activity relationship and docking studies in a series of anthocyanin derivatives as cytochrome P450 3A4 inhibitorsStructural and biophysical characterization of human cytochromes P450 2B6 and 2A6 bound to volatile hydrocarbons: analysis and comparison.Oxidation of methyl and ethyl nitrosamines by cytochrome P450 2E1 and 2B1Metabolic activation of polycyclic aromatic hydrocarbons and aryl and heterocyclic amines by human cytochromes P450 2A13 and 2A6.Conformational diversity and ligand tunnels of mammalian cytochrome P450s.Computational modelling of oxygenation processes in enzymes and biomimetic model complexes.Use of density functional theory in drug metabolism studies.Cytochrome P450 2A6 deletion polymorphism and risk of lung cancer: a meta-analysis.Oxidation of Acenaphthene and Acenaphthylene by Human Cytochrome P450 Enzymes.Binding free energies for nicotine analogs inhibiting cytochrome P450 2A6 by a combined use of molecular dynamics simulations and QM/MM-PBSA calculations.Toxicity of aerosols of nicotine and pyruvic acid (separate and combined) in Sprague-Dawley rats in a 28-day OECD 412 inhalation study and assessment of systems toxicology.Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene by human cytochrome P450 2A13Structure-Function Studies of Naphthalene, Phenanthrene, Biphenyl, and Their Derivatives in Interaction with and Oxidation by Cytochromes P450 2A13 and 2A6.Systems approaches evaluating the perturbation of xenobiotic metabolism in response to cigarette smoke exposure in nasal and bronchial tissues.Nicotine Component of Cigarette Smoke Extract (CSE) Decreases the Cytotoxicity of CSE in BEAS-2B Cells Stably Expressing Human Cytochrome P450 2A13.Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9.Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2',5'-Tetrachlorobiphenyl.Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants.Molecular Determinants of Substrate Affinity and Enzyme Activity of a Cytochrome P450 VariantStructure and Dynamics of Human Drug-Metabolizing Cytochrome P450 Enzymes
P2860
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P2860
Nicotine and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Binding and Access Channel in Human Cytochrome P450 2A6 and 2A13 Enzymes
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Nicotine and 4-(Methylnitrosam ...... rome P450 2A6 and 2A13 Enzymes
@ast
Nicotine and 4-(Methylnitrosam ...... rome P450 2A6 and 2A13 Enzymes
@en
Nicotine and 4-(Methylnitrosam ...... rome P450 2A6 and 2A13 Enzymes
@nl
type
label
Nicotine and 4-(Methylnitrosam ...... rome P450 2A6 and 2A13 Enzymes
@ast
Nicotine and 4-(Methylnitrosam ...... rome P450 2A6 and 2A13 Enzymes
@en
Nicotine and 4-(Methylnitrosam ...... rome P450 2A6 and 2A13 Enzymes
@nl
prefLabel
Nicotine and 4-(Methylnitrosam ...... rome P450 2A6 and 2A13 Enzymes
@ast
Nicotine and 4-(Methylnitrosam ...... rome P450 2A6 and 2A13 Enzymes
@en
Nicotine and 4-(Methylnitrosam ...... rome P450 2A6 and 2A13 Enzymes
@nl
P2860
P3181
P356
P1476
Nicotine and 4-(Methylnitrosam ...... rome P450 2A6 and 2A13 Enzymes
@en
P2093
Emily E Scott
Natasha M DeVore
P2860
P304
P3181
P356
10.1074/JBC.M112.372813
P407
P577
2012-08-03T00:00:00Z