Inhibition ofMycobacterium tuberculosisTransaminase BioA by Aryl Hydrazines and Hydrazides
about
Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.bioA mutant of Mycobacterium tuberculosis shows severe growth defect and imparts protection against tuberculosis in guinea pigs.Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA.Thermal proteome profiling monitors ligand interactions with cellular membrane proteins.In silico discovery and in vitro activity of inhibitors against Mycobacterium tuberculosis 7,8-diaminopelargonic acid synthase (Mtb BioA).Type-II NADH Dehydrogenase (NDH-2): a promising therapeutic target for antitubercular and antibacterial drug discovery.Disrupting the Constitutive, Homodimeric Protein-Protein Interface in CK2β Using a Biophysical Fragment-Based Approach.Rational Optimization of Mechanism-Based Inhibitors through Determination of the Microscopic Rate Constants of Inactivation.Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.Targeting protein biotinylation enhances tuberculosis chemotherapy.Identification of Mycobacterium tuberculosis BioA inhibitors by using structure-based virtual screening.
P2860
Q30393244-D52C55D6-3EC3-4EC8-B68B-75C52B1CD7DAQ33848397-D9859074-7390-404D-8560-FF31747ED7C5Q35661873-1118A57E-1EDF-4787-8799-47E20B6FF8F1Q35829229-FA583261-AFCA-482F-945D-9A97CA46E050Q37682685-41FB5593-4157-4C25-9127-75D6D15A689CQ39284340-1E0940D3-3CEB-45D5-A508-B9AD4B4B649CQ42154255-E3A8FFA7-3137-4CD3-A858-437B46A742B9Q48136170-FF45EAB9-2D76-4E66-BA1A-94E96EB31967Q48307368-7888ADF3-F7F0-4D9E-A2D3-5D3D9BE155D5Q52562988-7951ECB0-9ECB-493A-A701-2A7F503B3B1BQ55181809-D3B1C33B-FDEE-4086-8680-9011A479D082
P2860
Inhibition ofMycobacterium tuberculosisTransaminase BioA by Aryl Hydrazines and Hydrazides
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Inhibition ofMycobacterium tub ...... Aryl Hydrazines and Hydrazides
@ast
Inhibition ofMycobacterium tub ...... Aryl Hydrazines and Hydrazides
@en
Inhibition ofMycobacterium tub ...... Aryl Hydrazines and Hydrazides
@nl
type
label
Inhibition ofMycobacterium tub ...... Aryl Hydrazines and Hydrazides
@ast
Inhibition ofMycobacterium tub ...... Aryl Hydrazines and Hydrazides
@en
Inhibition ofMycobacterium tub ...... Aryl Hydrazines and Hydrazides
@nl
prefLabel
Inhibition ofMycobacterium tub ...... Aryl Hydrazines and Hydrazides
@ast
Inhibition ofMycobacterium tub ...... Aryl Hydrazines and Hydrazides
@en
Inhibition ofMycobacterium tub ...... Aryl Hydrazines and Hydrazides
@nl
P2093
P2860
P356
P1433
P1476
Inhibition of Mycobacterium tu ...... aryl hydrazines and hydrazides
@en
P2093
Courtney C Aldrich
Daniel J Wilson
Todd W Geders
P2860
P304
P356
10.1002/CBIC.201300748
P577
2014-01-31T00:00:00Z