Proof of principle for epitope-focused vaccine design - Test2 - elhamkhani - TriplyDB

Proof of principle for epitope-focused vaccine design

Proof of principle for epitope-focused vaccine design

http://www.wikidata.org/entity/Q27681593

about

The germinal center antibody response in health and disease Self-assembling protein nanoparticles in the design of vaccines Structural and Computational Biology in the Design of Immunogenic Vaccine Antigens Emerging Vaccine Technologies Paths to a malaria vaccine illuminated by parasite genomics A high-throughput shotgun mutagenesis approach to mapping B-cell antibody epitopes Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer Structure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial Virus Deconstructing the Antiviral Neutralizing-Antibody Response: Implications for Vaccine Development and Immunity A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells Applying contemporary immunology to elucidate heterologous effects of infant vaccines and to better inform maternal-infant immunization practices.Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G Reverse vaccinology 2.0: Human immunology instructs vaccine antigen design Analysis of Human RSV Immunity at the Molecular Level: Learning from the Past and Present Protein Crystallography in Vaccine Research and Development A Rationally Designed TNF-α Epitope-Scaffold Immunogen Induces Sustained Antibody Response and Alleviates Collagen-Induced Arthritis in Mice Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy Epitope specific T-cell responses against influenza A in a healthy population.Rapid search for tertiary fragments reveals protein sequence-structure relationships Computational tools for epitope vaccine design and evaluation Vaccines, new opportunities for a new society.Achievements and Challenges in Computational Protein Design.Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.Rapid fine conformational epitope mapping using comprehensive mutagenesis and deep sequencing.Classification of self-assembling protein nanoparticle architectures for applications in vaccine design Chimeric GII.4 norovirus virus-like-particle-based vaccines induce broadly blocking immune responses.Probing the Impact of Local Structural Dynamics of Conformational Epitopes on Antibody Recognition.Transplanting supersites of HIV-1 vulnerability.In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-Dimers.RNA virus reverse genetics and vaccine design.Options and obstacles for designing a universal influenza vaccine Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques.Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody Identification and validation of a linear protective neutralizing epitope in the β-pore domain of alpha toxin.Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose Palivizumab epitope-displaying virus-like particles protect rodents from RSV challenge.Affinity selection of epitope-based vaccines using a bacteriophage virus-like particle platform A site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgL.

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Proof of principle for epitope-focused vaccine design

http://www.wikidata.org/entity/Q27681593

description

2014 nî lūn-bûn

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2014 թուականի Մարտին հրատարակուած գիտական յօդուած

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2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Proof of principle for epitope-focused vaccine design

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Proof of principle for epitope-focused vaccine design

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Proof of principle for epitope-focused vaccine design

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type

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Proof of principle for epitope-focused vaccine design

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Proof of principle for epitope-focused vaccine design

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Proof of principle for epitope-focused vaccine design

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Proof of principle for epitope-focused vaccine design

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Proof of principle for epitope-focused vaccine design

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Proof of principle for epitope-focused vaccine design

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Alexandria Schroeter

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Andreia M Serra

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Bruno E Correia

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Colin Correnti

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Eric Stevens

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Gretchen Baneyx

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Joseph G Jardine

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Man Chen

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Margaret A Holmes

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Mary J Connell

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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

RosettaHoles2: a volumetric packing measure for protein structure refinement and validation

The global distribution and burden of dengue

Structural basis of respiratory syncytial virus neutralization by motavizumab

Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope

Elicitation of structure-specific antibodies by epitope scaffolds

Design and Characterization of Epitope-Scaffold Immunogens That Present the Motavizumab Epitope from Respiratory Syncytial Virus

Principles for designing ideal protein structures

Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold

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201-6

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10.1038/NATURE12966

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7491

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507

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James E. Crowe Jr.

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Barney S. Graham

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2014-03-13T00:00:00Z

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260116477

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1031434303

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