Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
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The roles of entropy and kinetics in structure predictionSampling realistic protein conformations using local structural biasExperimental illumination of a fitness landscapeFundamental challenges in mechanistic enzymology: progress toward understanding the rate enhancements of enzymesDoing molecular biophysics: finding, naming, and picturing signal within complexityDe novo computational design of retro-aldol enzymesParadigms for computational nucleic acid designHigh-resolution structural and thermodynamic analysis of extreme stabilization of human procarboxypeptidase by computational protein designImproved prediction of protein side-chain conformations with SCWRL4Critical assessment of methods of protein structure prediction-Round VIIHigh-resolution structure prediction and the crystallographic phase problemComputational design of Candida boidinii xylose reductase for altered cofactor specificityA composite score for predicting errors in protein structure modelsDesign of protein-ligand binding based on the molecular-mechanics energy modelRosettaDesign server for protein designPractical lessons from protein structure prediction.CAMPO, SCR_FIND and CHC_FIND: a suite of web tools for computational structural biology.Improvement in protein functional site prediction by distinguishing structural and functional constraints on protein family evolution using computational design.Assessing local structural perturbations in proteinsPrinciples and Overview of Sampling Methods for Modeling Macromolecular Structure and DynamicsFrom Mollusks to Medicine: A Venomics Approach for the Discovery and Characterization of Therapeutics from Terebridae Peptide ToxinsWhy reinvent the wheel? Building new proteins based on ready-made partsProtein stability: computation, sequence statistics, and new experimental methodsSelf-assembled bionanostructures: proteins following the lead of DNA nanostructuresMerging molecular mechanism and evolution: theory and computation at the interface of biophysics and evolutionary population geneticsUrzymology: experimental access to a key transition in the appearance of enzymesProtein design: toward functional metalloenzymesComputational modeling of membrane proteinsFunctional Class I and II Amino Acid-activating Enzymes Can Be Coded by Opposite Strands of the Same GeneFolding and Stabilization of Native-Sequence-Reversed Proteins.Structural Insights into the Evolution of a Non-Biological Protein: Importance of Surface Residues in Protein Fold OptimizationStructure-based Protocol for Identifying Mutations that Enhance Protein–Protein Binding AffinitiesComputational design and experimental study of tighter binding peptides to an inactivated mutant of HIV-1 proteaseStructure of a designed, right-handed coiled-coil tetramer containing all biological amino acidsHigh-resolution design of a protein loopImproving NMR protein structure quality by Rosetta refinement: A molecular replacement studyCrystal structure of an extensively simplified variant of bovine pancreatic trypsin inhibitor in which over one-third of the residues are alaninesComputer-Based Redesign of a β Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo β Sheet DesignAlteration of enzyme specificity by computational loop remodeling and designA Correspondence Between Solution-State Dynamics of an Individual Protein and the Sequence and Conformational Diversity of its Family
P2860
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P2860
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
@ast
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
@en
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
@en-gb
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
@nl
type
label
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
@ast
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
@en
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
@en-gb
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
@nl
altLabel
Design of a novel globular protein fold with atomic-level accuracy
@en
prefLabel
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
@ast
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
@en
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
@en-gb
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
@nl
P2093
P2860
P3181
P356
P1433
P1476
Design of a novel globular protein fold with atomic-level accuracy
@en
P2093
Barry L Stoddard
Brian Kuhlman
Gabriele Varani
Gregory C Ireton
P2860
P304
P3181
P356
10.1126/SCIENCE.1089427
P407
P577
2003-11-01T00:00:00Z