Tailoring small molecules for an allosteric site on procaspase-6
about
Caspase vinyl sulfone small molecule inhibitors prevent axonal degeneration in human neurons and reverse cognitive impairment in Caspase-6-overexpressing mice.Small Molecule Active Site Directed Tools for Studying Human CaspasesTwenty years on: the impact of fragments on drug discovery.Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein-Ligand ComplexesRare human Caspase-6-R65W and Caspase-6-G66R variants identify a novel regulatory region of Caspase-6 activity.
P2860
Tailoring small molecules for an allosteric site on procaspase-6
description
2014 nî lūn-bûn
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2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2014 թվականի հունվարին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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name
Tailoring small molecules for an allosteric site on procaspase-6
@ast
Tailoring small molecules for an allosteric site on procaspase-6
@en
Tailoring small molecules for an allosteric site on procaspase-6
@nl
type
label
Tailoring small molecules for an allosteric site on procaspase-6
@ast
Tailoring small molecules for an allosteric site on procaspase-6
@en
Tailoring small molecules for an allosteric site on procaspase-6
@nl
prefLabel
Tailoring small molecules for an allosteric site on procaspase-6
@ast
Tailoring small molecules for an allosteric site on procaspase-6
@en
Tailoring small molecules for an allosteric site on procaspase-6
@nl
P2093
P2860
P356
P1433
P1476
Tailoring small molecules for an allosteric site on procaspase-6
@en
P2093
Adam R Renslo
Anthony M Giannetti
Brandon Bravo
Brian R Hearn
Christine Pozniak
Christine Tam
Cuong Q Ly
Frederick Cohen
Jeremy Murray
Joe Lewcock
P2860
P304
P356
10.1002/CMDC.201300424
P577
2014-01-01T00:00:00Z