Crystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loop
about
Structure of a human carcinogen-converting enzyme, SULT1A1. Structural and kinetic implications of substrate inhibitionThe structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferaseCrystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferaseThe crystal structure of anthranilate phosphoribosyltransferase from the enterobacterium Pectobacterium carotovorumStructures of hypoxanthine-guanine phosphoribosyltransferase (TTHA0220) fromThermus thermophilusHB8Functional significance of four successive glycine residues in the pyrophosphate binding loop of fungal 6-oxopurine phosphoribosyltransferasesTargeting purine and pyrimidine metabolism in human apicomplexan parasitesThe biosynthetic pathway of 2-azahypoxanthine in fairy-ring forming fungus.The two toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase isozymes form heterotetramers.Virtual screening of combinatorial libraries across a gene family: in search of inhibitors of Giardia lamblia guanine phosphoribosyltransferase.Differential localization of alternatively spliced hypoxanthine-xanthine-guanine phosphoribosyltransferase isoforms in Toxoplasma gondii.Analysis of the assembly function of the human immunodeficiency virus type 1 gag protein nucleocapsid domain.Purine phosphoribosyltransferases.Positive evolutionary selection of an HD motif on Alzheimer precursor protein orthologues suggests a functional role.Induced fit in arginine kinase.Crystal structure of a predicted phosphoribosyltransferase (TT1426) from Thermus thermophilus HB8 at 2.01 A resolution.Screening for small molecule inhibitors of Toxoplasma gondii.Point mutations in the guanine phosphoribosyltransferase from Giardia lamblia modulate pyrophosphate binding and enzyme catalysis.Converting the guanine phosphoribosyltransferase from Giardia lamblia to a hypoxanthine-guanine phosphoribosyltransferase.Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.Crystal structure of glutamine phosphoribosylpyrophosphate amidotransferase from Escherichia coli.Different substrate recognition motifs of human and trypanosome nucleobase transporters. Selective uptake of purine antimetabolites.Purine salvage pathways in the apicomplexan parasite Toxoplasma gondii.Molecular, kinetic and thermodynamic characterization of Mycobacterium tuberculosis orotate phosphoribosyltransferase.Xanthine phosphoribosyltransferase from Leishmania donovani. Molecular cloning, biochemical characterization, and genetic analysis.The conserved serine-tyrosine dipeptide in Leishmania donovani hypoxanthine-guanine phosphoribosyltransferase is essential for catalytic activity.
P2860
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P2860
Crystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loop
description
1996 nî lūn-bûn
@nan
1996 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Crystal structures of Toxoplas ...... c role of a long flexible loop
@ast
Crystal structures of Toxoplas ...... c role of a long flexible loop
@en
Crystal structures of Toxoplas ...... c role of a long flexible loop
@nl
type
label
Crystal structures of Toxoplas ...... c role of a long flexible loop
@ast
Crystal structures of Toxoplas ...... c role of a long flexible loop
@en
Crystal structures of Toxoplas ...... c role of a long flexible loop
@nl
prefLabel
Crystal structures of Toxoplas ...... c role of a long flexible loop
@ast
Crystal structures of Toxoplas ...... c role of a long flexible loop
@en
Crystal structures of Toxoplas ...... c role of a long flexible loop
@nl
P2093
P2860
P356
P1476
Crystal structures of Toxoplas ...... c role of a long flexible loop
@en
P2093
M A Schumacher
R G Brennan
P2860
P356
10.1038/NSB1096-881
P577
1996-10-01T00:00:00Z